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- 抗原 See all SLC39A8 抗体
- SLC39A8 (Solute Carrier Family 39 (Zinc Transporter), Member 8 (SLC39A8))
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抗原表位
- AA 221-234, Extracellular
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SLC39A8 antibody is conjugated to FITC
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应用范围
- Flow Cytometry (FACS)
- 原理
- A Rabbit Polyclonal Antibody to Zinc Transporter ZIP8 Conjugated to the Fluorescent Dye FITC
- 特异性
- 2nd extracellular loop
- 交叉反应
- 人, 小鼠, 大鼠
- 预测反应
- Mouse - identical, Human - 12,14 amino acid residues identical
- 产品特性
- Anti-ZIP8 (SLC39A8) (extracellular) Antibody (ABIN7043726, ABIN7045350 and ABIN7045351) is a highly specific antibody directed against an epitope of the rat Zinc transporter ZIP8. The antibody can be used in western blot, immunohistochemistry, and indirect live cell flow cytometry. It has been designed to recognize ZIP8 from human, rat, and mouse samples. \nAnti-ZIP8 (SLC39A8) (extracellular)-FITC Antibody (ABIN7043726, ABIN7045350 and ABIN7045351)-F) is directly conjugated to fluorescein isothiocyanate (FITC). The antibody can be used in immunofluorescent applications such as direct live cell flow cytometry.
- 纯化方法
- Affinity purified on immobilized antigen.
- 免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: (C)KTYGQNDHTHFRND, corresponding to amino acid residues 221-234 of rat ZIP8
- 亚型
- IgG
- Top Product
- Discover our top product SLC39A8 Primary Antibody
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anti-Solute Carrier Family 39 (Zinc Transporter), Member 8 (SLC39A8) (AA 221-234), (Extracellular) antibody
SLC39A8 适用: 大鼠 WB, IHC, FACS, IF, LCI 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 39 (Zinc Transporter), Member 8 (SLC39A8) (AA 30-132) antibodySLC39A8 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 39 (Zinc Transporter), Member 8 (SLC39A8) (Internal Region) antibodySLC39A8 适用: 人 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 39 (Zinc Transporter), Member 8 (SLC39A8) (AA 180-300) antibodySLC39A8 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 39 (Zinc Transporter), Member 8 (SLC39A8) (N-Term) antibodySLC39A8 适用: 人, 马, 犬, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 39 (Zinc Transporter), Member 8 (SLC39A8) (AA 107-156) antibodySLC39A8 适用: 人, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 39 (Zinc Transporter), Member 8 (SLC39A8) (AA 218-246) antibodySLC39A8 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB24763 unconjugated
anti-Solute Carrier Family 39 (Zinc Transporter), Member 8 (SLC39A8) (AA 225-254), (Middle Region) antibodySLC39A8 适用: 人 WB, FACS, EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: N/A
Application Dilutions Western blot wb: N/A
- 说明
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Negative Control: (ABIN7582044)
Blocking Peptide: (ABIN7237102)
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- 50 μL double distilled water (DDW).
- 浓度
- 1 mg/mL
- 缓冲液
- PBS pH 7.4, 1 % BSA with 0.05 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C, protected from the light, for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- 抗原
- SLC39A8 (Solute Carrier Family 39 (Zinc Transporter), Member 8 (SLC39A8))
- 别名
- SLC39A8 (SLC39A8 产品)
- 背景
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Zinc transporter ZIP8, Zrt- and Irt-like protein 8, Solute carrier family 39 member 8, BIGM103,Zinc uptake transporter, ZIP8, belongs to the SLC39 transporter family. ZIP transporters are responsible for zinc transport into the cytoplasm across cellular membranes, either influx from the extracellular space or efflux from intracellular organelles. Regulation and maintenance of proper concentration and distribution of cellular zinc nutrient by ZIP transporters are essential to the function, metabolism, growth, proliferation and survival of cells1,2.ZIP structure contains eight predicted transmembrane (TM) domains while the N- and C-termini are extracellular. A long loop region is present between TM3 and TM4 domains, harboring a histidine-rich region. TM4 and TM5 domains are amphipathic and are thought to form a cavity through which metals are transported1.ZIP8 protein is encoded by the SLC39A8 gene and is highly expressed in T cells. ZIP8 also plays an important role at the onset of inflammation2.Zinc deficiency can cause growth retardation, cognitive impairment, metabolic disorders, infertility, dysfunction of the immune system, abnormalities in T-cells, natural killer cells and monocytes, and reduction in antibody formation1,2. Studies exploring knockdown of ZIP8 protein show a reduction of cellular zinc content, impaired mitochondrial function in response to TNF-α and increased cell death2.
Alternative names: ZIP8 (SLC39A8), Zinc transporter ZIP8, Zrt- and Irt-like protein 8, Solute carrier family 39 member 8, BIGM103 - 基因ID
- 295455
- NCBI登录号
- NM_022154
- UniProt
- Q5FVQ0
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