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GLUT1 抗体 (Extracellular)

SLC2A1 适用: 大鼠 WB, FACS 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7043692
发货至: 中国
  • 抗原 See all GLUT1 (SLC2A1) 抗体
    GLUT1 (SLC2A1) (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 1 (SLC2A1))
    抗原表位
    • 9
    • 9
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 41-55, Extracellular
    适用
    • 76
    • 42
    • 41
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    大鼠
    宿主
    • 63
    • 11
    • 6
    克隆类型
    • 54
    • 26
    多克隆
    标记
    • 51
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This GLUT1 antibody is un-conjugated
    应用范围
    • 50
    • 32
    • 27
    • 17
    • 15
    • 15
    • 11
    • 8
    • 6
    • 6
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    原理
    A Rabbit Polyclonal Antibody to Glucose Transporter 1
    特异性
    1st extracellular loop
    交叉反应
    人, 小鼠, 大鼠
    预测反应
    Mouse,human - 14 out of 15 amino acid residues identical
    产品特性
    Anti-GLUT1 (extracellular) Antibody (ABIN7043692, ABIN7044497 and ABIN7044498) is a highly specific antibody directed against an epitope of the rat protein. The antibody can be used in western blot and indirect live cell flow cytometry applications. It has been designed to recognize GLUT1 from human, rat, and mouse samples.
    纯化方法
    Affinity purified on immobilized antigen.
    免疫原

    Immunogen: Synthetic peptide

    Immunogen Sequence: (C)EEFYNQTWNHRYGES, corresponding to amino acid residues 41-55 of rat Glucose transporter 1

    亚型
    IgG
    Top Product
    Discover our top product SLC2A1 Primary Antibody
  • 应用备注

    Antigen preadsorption control: 1 μg peptide per 1 μg antibody

    Application Dilutions Immunohistochemistry paraffin embedded sections ihc: N/A

    Application Dilutions Western blot wb: 1:400

    说明

    Negative Control: (ABIN7236994)

    Blocking Peptide: (ABIN7236994)

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    0.2 mL double distilled water (DDW).
    浓度
    1 mg/mL
    缓冲液
    PBS pH 7.4
    储存条件
    4 °C,-20 °C
    储存方法

    Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.

    Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

  • 抗原
    GLUT1 (SLC2A1) (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 1 (SLC2A1))
    别名
    SLC2A1 (SLC2A1 产品)
    背景
    Glucose transporter 1, Facilitated glucose transporter member 1, SLC2A1,Glucose transporter 1 (GLUT1) belongs to the major facilitator superfamily (MFS). It is encoded by SLC2A1, and mediates basal-level cellular uptake of glucose into many tissues. GLUT1 contains 12 membrane-spanning domains with both the amino and carboxyl termini oriented intracellularly. In addition, a single extracellular N-linked glycosylation site is present1.GLUT1 is widely expressed, but it is most abundant in fibroblasts, erythrocytes, and endothelial cells with low levels of expression in muscle, liver, and adipose tissue2.Inactivating mutations of GLUT1, resulting in compromised transport activities for glucose, are associated with diseases as a result of lack of energy supply to the brain3. GLUT1 deficiency syndrome (also known as De Vivo syndrome) is characterized by a spectrum of symptoms including early-onset seizures, microcephaly and retarded development4. In addition, elevated expression levels of GLUT1 have been observed in several cancer types, identifying GLUT1 as an important prognostic indicator for tumorigenesis5.

    Alternative names: GLUT1, Glucose transporter 1, Facilitated glucose transporter member 1, SLC2A1
    基因ID
    24778
    NCBI登录号
    NM_006516
    UniProt
    P11167
    途径
    Sensory Perception of Sound, Dicarboxylic Acid Transport, Warburg Effect
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