ATP1A1 抗体 (Intracellular)
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- 抗原 See all ATP1A1 抗体
- ATP1A1 (Sodium Potassium ATPase, alpha1 (ATP1A1))
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抗原表位
- AA 7-20, Intracellular
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ATP1A1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- 原理
- A Rabbit Polyclonal Antibody to Alpha 1 Na+/K+ ATPase
- 特异性
- Intracellular, N-terminus
- 交叉反应
- 人, 小鼠, 大鼠
- 预测反应
- Mouse,dog,pig - identical, Human- 13,14 amino acid residues identical
- 产品特性
- Anti-Alpha 1 Na+/K+ ATPase Antibody (ABIN7043659, ABIN7044637 and ABIN7044638)) is a highly specific antibody directed against an epitope of the rat ATP1A1. The antibody can be used in western blot and immunohistochemistry applications. It has been designed to recognize ATP1A1 from rat, mouse, and human samples.
- 纯化方法
- Affinity purified on immobilized antigen.
- 免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: (C)RDKYEPAAVSEHGD, corresponding to amino acid residues 7- 20 of rat ATP1A1
- 亚型
- IgG
- Top Product
- Discover our top product ATP1A1 Primary Antibody
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anti-Sodium Potassium ATPase, alpha1 (ATP1A1) (N-Term) antibody
ATP1A1 适用: 人 WB 宿主: 山羊 Polyclonal unconjugated
anti-Sodium Potassium ATPase, alpha1 (ATP1A1) (N-Term) antibodyATP1A1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sodium Potassium ATPase, alpha1 (ATP1A1) antibodyATP1A1 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Sodium Potassium ATPase, alpha1 (ATP1A1) (pTyr10) antibodyATP1A1 适用: 人 WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Sodium Potassium ATPase, alpha1 (ATP1A1) (AA 493-660) antibodyATP1A1 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal unconjugated
anti-Sodium Potassium ATPase, alpha1 (ATP1A1) (AA 493-660) antibodyATP1A1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sodium Potassium ATPase, alpha1 (ATP1A1) (AA 225-407) antibodyATP1A1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Sodium Potassium ATPase, alpha1 (ATP1A1) (pSer16) antibodyATP1A1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sodium Potassium ATPase, alpha1 (ATP1A1) (AA 1-100) antibodyATP1A1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sodium Potassium ATPase, alpha1 (ATP1A1) (Ser23) antibodyATP1A1 适用: 大鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:200-1:400
Application Dilutions Western blot wb: 1:200
- 说明
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Negative Control: BLP-NP001
Blocking Peptide: BLP-NP001
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Recosntitute with double distilled water (DDW) to a concentration of 1.0 mg/mL.
- 浓度
- 1 mg/mL
- 缓冲液
- PBS pH 7.4
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- 抗原
- ATP1A1 (Sodium Potassium ATPase, alpha1 (ATP1A1))
- 别名
- ATP1A1 (ATP1A1 产品)
- 背景
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ATP1A1, Sodium/potassium ATPase catalytic subunit alpha-1, Sodium pump subunit alpha-1,Na+/K+-ATPase, a membrane protein located on the plasma membrane of all animal cells, is involved in maintaining the Na+ and K+ gradients across the cell membrane1. It is ubiquitously expressed in neurons and helps maintain normal neuronal function2. The enzyme is composed of a catalytic α chain of 112 kDa. and α glycosylated β chain of 40-50 kDa. There are four isoforms of the α subunit (α1, α2, α3 and α4) and three isoforms of the β subunit (β1, β2 and β3) with different tissue distributions3. The N-terminus is located on the cytoplasmic side of the membrane. There are four transmembrane segments in the first third of the polypeptide chain, a large cytoplasmic loop (LCL) comprising the second third of the chain and four to six transmembrane segments in the C-terminal third of the protein with the C-terminus also on the cytoplasmic side of the membrane4. Na+/K+-ATPase abnormalities have been reported to be involved in several neurological diseases such as seizures, bipolar disorder, spongiform encephalopathy, and Alzheimer's disease. Na+/K+-ATPase may also have implications in behavioral defects5.
Alternative names: Alpha 1 Na+/K+ ATPase, ATP1A1, Sodium/potassium ATPase catalytic subunit alpha-1, Sodium pump subunit alpha-1 - 基因ID
- 24211
- NCBI登录号
- NM_001160233
- UniProt
- P06685
- 途径
- Thyroid Hormone Synthesis, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Proton Transport, Ribonucleoside Biosynthetic Process
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