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ATP1A1 抗体 (Intracellular)

Name: ATP1A1 抗体 (Intracellular)
SKU: ABIN7043659
Availability: OutOfStock

This anti-ATP1A1 antibody is a 兔多克隆 antibody detecting ATP1A1 in WB, IHC 和 IF. Suitable for 大鼠.

Western blot analysis of human Colo-205 colon adenocarcinoma cell lysate: - 1. (ATP1A1 抗体 (Intracellular))

Expression of Na+/K+ ATPase α1 (ATP1A1) in rat kidney - Immunohistochemical staining of paraffin embedded rat kidney sections using Anti-Alpha 1 Na+/K+ ATPase Antibody (ABIN7043659, ABIN7044637 and ABIN7044638), (1:200). (ATP1A1 抗体 (Intracellular))

IHC

Expression of Na+/K+ ATPase α1 (ATP1A1) in mouse brain - Immunohistochemical staining of immersion-fixed, free floating mouse brain frozen sections using Anti-Alpha 1 Na+/K+ ATPase Antibody (ABIN7043659, ABIN7044637 and ABIN7044638), (1:400). (ATP1A1 抗体 (Intracellular))

IHC

Western blot analysis of rat (lanes 1 and 3) and mouse (lanes 2 and 4) brain membranes: - 1,2. (ATP1A1 抗体 (Intracellular))

4 images

产品编号 ABIN7043659

发货至: 中国

Datasheet as PDF

Quick Overview for ATP1A1 抗体 (Intracellular) (ABIN7043659)

抗原

See all ATP1A1 抗体

ATP1A1 (Sodium Potassium ATPase, alpha1 (ATP1A1))

适用

大鼠

宿主

兔

克隆类型

多克隆

标记

This ATP1A1 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Discover our top product ATP1A1 Primary Antibody

抗原表位
15

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7

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2

1

1

1

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AA 7-20, Intracellular

原理

A Rabbit Polyclonal Antibody to Alpha 1 Na+/K+ ATPase

特异性

Intracellular, N-terminus

交叉反应

人, 小鼠, 大鼠

预测反应

Mouse,dog,pig - identical, Human- 13,14 amino acid residues identical

产品特性

Anti-Alpha 1 Na+/K+ ATPase Antibody (ABIN7043659, ABIN7044637 and ABIN7044638) is a highly specific antibody directed against an epitope of the rat ATP1A1. The antibody can be used in western blot and immunohistochemistry applications. It has been designed to recognize ATP1A1 from rat, mouse, and human samples.

纯化方法

Affinity purified on immobilized antigen.

免疫原

Immunogen: Synthetic peptide
Immunogen Sequence: (C)RDKYEPAAVSEHGD, corresponding to amino acid residues 7- 20 of rat ATP1A1

亚型

IgG
anti-Sodium Potassium ATPase, alpha1 (ATP1A1) (N-Term) antibody
ATP1A1 适用: 人 WB 宿主: 山羊 Polyclonal unconjugated

anti-Sodium Potassium ATPase, alpha1 (ATP1A1) (N-Term) antibody
ATP1A1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Sodium Potassium ATPase, alpha1 (ATP1A1) antibody
ATP1A1 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated

anti-Sodium Potassium ATPase, alpha1 (ATP1A1) (pTyr10) antibody
ATP1A1 适用: 人 WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Sodium Potassium ATPase, alpha1 (ATP1A1) (AA 493-660) antibody
ATP1A1 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C206 unconjugated

anti-Sodium Potassium ATPase, alpha1 (ATP1A1) (AA 493-660) antibody
ATP1A1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Sodium Potassium ATPase, alpha1 (ATP1A1) (AA 225-407) antibody
ATP1A1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Sodium Potassium ATPase, alpha1 (ATP1A1) (pSer16) antibody
ATP1A1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Sodium Potassium ATPase, alpha1 (ATP1A1) (AA 1-100) antibody
ATP1A1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Sodium Potassium ATPase, alpha1 (ATP1A1) (Ser23) antibody
ATP1A1 适用: 大鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated

应用备注

Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:200-1:400
Application Dilutions Western blot wb: 1:200

说明

Negative Control: (ABIN7236890)
Blocking Peptide: (ABIN7236890)

限制

仅限研究用
状态

Lyophilized

溶解方式

Recosntitute with double distilled water (DDW) to a concentration of 1.0 mg/mL.

浓度

1 mg/mL

缓冲液

PBS pH 7.4

储存条件

4 °C,-20 °C

储存方法

Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
抗原

ATP1A1 (Sodium Potassium ATPase, alpha1 (ATP1A1))

别名

ATP1A1

背景

ATP1A1, Sodium/potassium ATPase catalytic subunit alpha-1, Sodium pump subunit alpha-1,Na+/K+-ATPase, a membrane protein located on the plasma membrane of all animal cells, is involved in maintaining the Na+ and K+ gradients across the cell membrane1. It is ubiquitously expressed in neurons and helps maintain normal neuronal function2. The enzyme is composed of a catalytic α chain of 112 kDa. and α glycosylated β chain of 40-50 kDa. There are four isoforms of the α subunit (α1, α2, α3 and α4) and three isoforms of the β subunit (β1, β2 and β3) with different tissue distributions3. The N-terminus is located on the cytoplasmic side of the membrane. There are four transmembrane segments in the first third of the polypeptide chain, a large cytoplasmic loop (LCL) comprising the second third of the chain and four to six transmembrane segments in the C-terminal third of the protein with the C-terminus also on the cytoplasmic side of the membrane4. Na+/K+-ATPase abnormalities have been reported to be involved in several neurological diseases such as seizures, bipolar disorder, spongiform encephalopathy, and Alzheimer's disease. Na+/K+-ATPase may also have implications in behavioral defects5.

Alternative names: Alpha 1 Na+/K+ ATPase, ATP1A1, Sodium/potassium ATPase catalytic subunit alpha-1, Sodium pump subunit alpha-1

基因ID

24211

NCBI登录号

NM_001160233

UniProt

P06685

途径

Thyroid Hormone Synthesis, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Proton Transport, Ribonucleoside Biosynthetic Process