SCN11A 抗体 (Intracellular)
-
- 抗原 See all SCN11A 抗体
- SCN11A (Sodium Channel, Voltage-Gated, Type XI, alpha Subunit (SCN11A))
-
抗原表位
- AA 1748-1765, Intracellular
-
适用
- 大鼠
-
宿主
-
豚鼠
-
克隆类型
- 多克隆
-
标记
- This SCN11A antibody is un-conjugated
-
应用范围
- Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF)
- 原理
- A Guinea Pig Polyclonal Antibody to SCN11A (NaV1.9) Channel
- 特异性
- Intracellular, C-terminus
- 预测反应
- 18 amino acid residues identical, human - 14,Mouse - 15
- 产品特性
- Guinea pig Anti-SCN11A (Nav1.9) Antibody is directed against an epitope of the rat protein. Guinea pig Anti-SCN11A (NaV1.9) Antibody , raised in guinea pigs, can be used in western blot and immunohistochemical applications, and has been designed to recognize NaV1.9 from mouse, rat and human samples. The antigen used to immunize guinea pigs is the same as Anti-SCN11A (NaV1.9) Antibody (ABIN7043657, ABIN7045241 and ABIN7045242) raised in rabbit. Our line of guinea pig antibodies enables more flexibility with our products such as multiplex staining studies, immunoprecipitation, etc.
- 纯化方法
- Affinity purified on immobilized antigen.
- 免疫原
-
Immunogen: Synthetic peptide
Immunogen Sequence: CNGDLSSLDVAKVKVHND, corresponding to amino acid residues 1748-1765 of rat NaV1.9
- 亚型
- IgG
- Top Product
- Discover our top product SCN11A Primary Antibody
-
anti-Sodium Channel, Voltage-Gated, Type XI, alpha Subunit (SCN11A) (AA 403-551) antibody
SCN11A 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Sodium Channel, Voltage-Gated, Type XI, alpha Subunit (SCN11A) antibodySCN11A 适用: 人, 大鼠, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sodium Channel, Voltage-Gated, Type XI, alpha Subunit (SCN11A) (AA 1726-1791) antibodySCN11A 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 2B10 unconjugated
anti-Sodium Channel, Voltage-Gated, Type XI, alpha Subunit (SCN11A) (Internal Region) antibodySCN11A 适用: 人 ELISA, WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sodium Channel, Voltage-Gated, Type XI, alpha Subunit (SCN11A) (AA 1748-1765), (Intracellular) antibodySCN11A 适用: 大鼠 IHC, WB, IF, IC 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: N/A
Application Dilutions Western blot wb: 1:200
- 说明
-
Negative Control: (ABIN7236878)
Blocking Peptide: (ABIN7236878)
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- 0.2 mL double distilled water (DDW).
- 浓度
- 1 mg/mL
- 缓冲液
- PBS pH 7.4
- 储存条件
- 4 °C,-20 °C
- 储存方法
-
Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
-
- 抗原
- SCN11A (Sodium Channel, Voltage-Gated, Type XI, alpha Subunit (SCN11A))
- 别名
- SCN11A (SCN11A 产品)
- 背景
-
PN5, SNS2, NAN, Sodium channel protein type 11 subunit alpha,Voltage-gated Na+ channels (NaV) are essential for the generation of action potentials and for cell excitability1. NaV channels are activated in response to depolarization and selectively allow the flow of Na+ ions. To date, nine NaV α subunits have been cloned and named NaV1.1-1.92,3. Their expression is developmentally and tissue specific.NaV channels are classified into two groups according to their sensitivity to tetrodotoxin (TTX): TTX-sensitive and TTX-resistant channels4,5. TTX-resistant channels have been suggested to play an important role in nociceptive transmission. Two TTX-resistant NaV channels are expressed in dorsal root ganglion (DRG) neurons, NaV1.8 and NaV1.9. The NaV1.9 channel (also called SCN11A, NAN or SNS2) is preferentially expressed in small-diameter DRG neurons4,5.Recently, it has been shown that BDNF activated NaV1.9 channels in the hippocampus suggesting that its expression is not restricted to DRG alone6.
Alternative names: SCN11A (NaV1.9), PN5, SNS2, NAN, Sodium channel protein type 11 subunit alpha - 基因ID
- 29701
- NCBI登录号
- NM_014139
- UniProt
- O88457
-
