Serotonin Receptor 1A 抗体 (AA 251-266)
Quick Overview for Serotonin Receptor 1A 抗体 (AA 251-266) (ABIN7043615)
抗原
See all Serotonin Receptor 1A (HTR1A) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 251-266
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原理
- A Rabbit Polyclonal Antibody to 5-Hydroxytryptamine Receptor 1A
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特异性
- 3rd intracellular loop
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交叉反应
- 小鼠, 大鼠
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交叉反应 （详细）
- Will not recognize human 5-hydroxytryptamine receptor 1A.
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预测反应
- Mouse - identical
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产品特性
- Anti-5HT1A Receptor (HTR1A) Antibody is directed against an intracellular epitope of the rat 5-Hydroxytryptamine receptor 1A. Anti-5HT1A Receptor (HTR1A) Antibody (ABIN7043615, ABIN7045278 and ABIN7045279) can be used for western blot and immunohistochemistry applications. It has been designed to recognize 5HT1A receptor from rat and mouse samples.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: KKSLNGQPGSGDWRRC, corresponding to amino acid residues 251-266 of rat 5-Hydroxytryptamine receptor 1A
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亚型
- IgG
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anti-Serotonin Receptor 1A (HTR1A) antibody
HTR1A 适用: 人 WB, IF, ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Serotonin Receptor 1A (HTR1A) (AA 301-400) antibodyHTR1A 适用: 人, 大鼠, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Serotonin Receptor 1A (HTR1A) (N-Term) antibodyHTR1A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Serotonin Receptor 1A (HTR1A) antibodyMicroarray verified HTR1A 适用: 人 IHC 宿主: 小鼠 Monoclonal MAB765230 unconjugated
anti-Serotonin Receptor 1A (HTR1A) antibodyMicroarray verified HTR1A 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB759700 unconjugated
anti-Serotonin Receptor 1A (HTR1A) (AA 230-334) antibodyHTR1A 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Serotonin Receptor 1A (HTR1A) (AA 239-273) antibodyHTR1A 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB46792 unconjugated
anti-Serotonin Receptor 1A (HTR1A) (N-Term) antibodyHTR1A 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Serotonin Receptor 1A (HTR1A) antibodyMicroarray verified HTR1A 适用: 人 IHC 宿主: 小鼠 Monoclonal MAB289500 unconjugated
anti-Serotonin Receptor 1A (HTR1A) (Internal Region) antibodyHTR1A 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:100
Application Dilutions Western blot wb: 1:200
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说明
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Cited Application: IP
Negative Control: (ABIN7236780)
Blocking Peptide: (ABIN7236780)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 0.2 mL double distilled water (DDW).
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4
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储存条件
- 4 °C,-20 °C
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储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- Serotonin Receptor 1A (HTR1A)
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别名
- HTR1A
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背景
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5-Hydroxytryptamine receptor 1A, Serotonin receptor 1A,Serotonin (5-hydroxytryptamine, 5-HT1) is an important neurotransmitter in the central nervous system (CNS) that exerts its neuronal activity via 5-HT receptors.5-HT receptors are subdivided into seven families termed 5-HT1 through 5-HT7.1 The 5-HT receptor families belong to the G-protein coupled receptor superfamily with the exception of 5-HT3 receptor class which belongs to the ligand-gated ion channels.2The 5-HT1 receptor class comprises of five different receptors (5-HT1A, 5-HT1B, 5-HT1D, 5-HT1E and 5-HT1F) which share 41-63 % overall sequence identity and couple preferentially to Gi/Go to inhibit cAMP formation.2The 5-HT1A receptor is the most widespread of all the 5-HT receptors. In the CNS, 5-HT1A receptors exist in the cerebral cortex, hippocampus, septum, amygdala and raphe nucelus in high densities, and was also demonstrated in a variety of tissues from various species.2,3 Activation of 5-HT1A receptor decreases blood pressure and heart rate, and is involved in learning, memory, relieving anxiety and depression.1,4
Alternative names: 5HT1A Receptor (HTR1A), 5-Hydroxytryptamine receptor 1A, Serotonin receptor 1A -
基因ID
- 24473
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NCBI登录号
- NM_000524
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UniProt
- P19327
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途径
- JAK/STAT Signaling, Synaptic Membrane, Feeding Behaviour
抗原
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