Serotonin Receptor 1A 抗体 (AA 251-266)
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- 抗原 See all Serotonin Receptor 1A (HTR1A) 抗体
- Serotonin Receptor 1A (HTR1A)
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抗原表位
- AA 251-266
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Serotonin Receptor 1A antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- 原理
- A Rabbit Polyclonal Antibody to 5-Hydroxytryptamine Receptor 1A
- 特异性
- 3rd intracellular loop
- 交叉反应
- 小鼠, 大鼠
- 交叉反应 (详细)
- Will not recognize human 5-hydroxytryptamine receptor 1A.
- 预测反应
- Mouse - identical
- 产品特性
- Anti-5HT1A Receptor (HTR1A) Antibody is directed against an intracellular epitope of the rat 5-Hydroxytryptamine receptor 1A. Anti-5HT1A Receptor (HTR1A) Antibody (ABIN7043615, ABIN7045278 and ABIN7045279)) can be used for western blot and immunohistochemistry applications. It has been designed to recognize 5HT1A receptor from rat and mouse samples.
- 纯化方法
- Affinity purified on immobilized antigen.
- 免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: KKSLNGQPGSGDWRRC, corresponding to amino acid residues 251-266 of rat 5-Hydroxytryptamine receptor 1A
- 亚型
- IgG
- Top Product
- Discover our top product HTR1A Primary Antibody
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- 应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:100
Application Dilutions Western blot wb: 1:200
- 说明
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Cited Application: IP
Negative Control: BLP-SR021
Blocking Peptide: BLP-SR021
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- 0.2 mL double distilled water (DDW).
- 浓度
- 1 mg/mL
- 缓冲液
- PBS pH 7.4
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- 抗原
- Serotonin Receptor 1A (HTR1A)
- 别名
- HTR1A (HTR1A 产品)
- 背景
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5-Hydroxytryptamine receptor 1A, Serotonin receptor 1A,Serotonin (5-hydroxytryptamine, 5-HT1) is an important neurotransmitter in the central nervous system (CNS) that exerts its neuronal activity via 5-HT receptors.5-HT receptors are subdivided into seven families termed 5-HT1 through 5-HT7.1 The 5-HT receptor families belong to the G-protein coupled receptor superfamily with the exception of 5-HT3 receptor class which belongs to the ligand-gated ion channels.2The 5-HT1 receptor class comprises of five different receptors (5-HT1A, 5-HT1B, 5-HT1D, 5-HT1E and 5-HT1F) which share 41-63 % overall sequence identity and couple preferentially to Gi/Go to inhibit cAMP formation.2The 5-HT1A receptor is the most widespread of all the 5-HT receptors. In the CNS, 5-HT1A receptors exist in the cerebral cortex, hippocampus, septum, amygdala and raphe nucelus in high densities, and was also demonstrated in a variety of tissues from various species.2,3 Activation of 5-HT1A receptor decreases blood pressure and heart rate, and is involved in learning, memory, relieving anxiety and depression.1,4
Alternative names: 5HT1A Receptor (HTR1A), 5-Hydroxytryptamine receptor 1A, Serotonin receptor 1A - 基因ID
- 24473
- NCBI登录号
- NM_000524
- UniProt
- P19327
- 途径
- JAK/STAT Signaling, Synaptic Membrane, Feeding Behaviour
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