P2RX7 抗体 (Intracellular)
Quick Overview for P2RX7 抗体 (Intracellular) (ABIN7043576)
抗原
See all P2RX7 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 576-595, Intracellular
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原理
- A Rabbit Polyclonal Antibody to P2X7 Receptor
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特异性
- Intracellular, C-terminus
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- human - 16,20 amino acid residues identical,Mouse - 18
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产品特性
- Anti-P2X7 Receptor Antibody (ABIN7043576, ABIN7045076 and ABIN7045077) is a highly specific antibody directed against an epitope of the rat protein. The antibody can be used in western blot, immunoprecipitation, immunocytochemistry, and immunohistochemistry applications. It has been designed to recognize P2X7 purinergic receptor from rat, mouse, and human samples.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: (C)KIRKEFPKTQGQYSGFKYPY, corresponding to amino acid residues 576-595 of rat P2X7 receptor
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亚型
- IgG
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anti-Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) (AA 226-452) antibody
P2RX7 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 7G1D6 unconjugated
anti-Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) (Center) antibodyP2RX7 适用: 人, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) (N-Term) antibodyP2RX7 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) (AA 136-152), (Extracellular) antibodyKO Validated P2RX7 适用: 小鼠 WB, IHC, FACS, IF, IC, LCI 宿主: 兔 Polyclonal unconjugated
anti-Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) (AA 136-152), (Extracellular) antibody (FITC)KO Validated P2RX7 适用: 小鼠 FACS, IF, IC, LCI 宿主: 兔 Polyclonal FITC
anti-Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) (AA 47-334) antibodyP2RX7 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) (Internal Region) antibodyP2RX7 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) (N-Term) antibodyVerified P2RX7 适用: 人, 小鼠 WB, IHC, ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) (C-Term) antibodyP2RX7 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) (N-Term) antibodyP2RX7 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:50
Application Dilutions Western blot wb: 1:200
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说明
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Cited Application: IP|IHC|ICC|IFC
Negative Control: (ABIN7236672)
Blocking Peptide: (ABIN7236672)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 0.2 mL double distilled water (DDW).
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4
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储存条件
- 4 °C,-20 °C
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储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- P2RX7 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7))
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别名
- P2RX7
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背景
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Purinergic receptor P2X7, P2RX7, P2Z, ATP receptor,The P2X7 purinergic receptor is a member of the ionotropic P2X receptor family that is activated by ATP. To date, this family consists of seven receptor subtypes, named P2X1-P2X7, all of which have been cloned.The various P2X receptors show distinct expression patterns. P2X1-6 receptors have been found in the central and peripheral nervous system, while the P2X7 receptor is found in cells of the immune system, particularly in antigen-presenting cells and microglia.The P2X7 receptor mediates the release of proinflamatory cytokines and stimulation of transcription factors and may also play an important role in apoptosis.1-3
Alternative names: P2X7 Receptor, Purinergic receptor P2X7, P2RX7, P2Z, ATP receptor -
基因ID
- 29665
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NCBI登录号
- NM_002562
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UniProt
- Q64663
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Vesicle Exocytosis
抗原
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