P2RX1 抗体 (Extracellular)
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- 抗原 See all P2RX1 抗体
- P2RX1 (Purinergic Receptor P2X, Ligand Gated Ion Channel 1 (P2RX1))
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抗原表位
- AA 270-283, Extracellular
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This P2RX1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF), Live Cell Imaging (LCI), Immunochromatography (IC)
- 原理
- A Rabbit Polyclonal Antibody to P2X1 Receptor
- 特异性
- Extracellular loop
- 交叉反应
- 人, 小鼠, 大鼠
- 预测反应
- Rat,mouse - 11,14 amino acid residues identical
- 产品特性
- Anti-P2X1 Receptor (extracellular) Antibody (ABIN7043571, ABIN7045096 and ABIN7045097) is a highly specific antibody directed against an epitope of the human protein. The antibody can be used in western blot, immunocytochemistry, immunohistochemistry, and indirect flow cytometry applications. It has been designed to recognize P2X1 receptor from rat, mouse, and human samples.
- 纯化方法
- Affinity purified on immobilized antigen.
- 免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: CRPIYEFHGLYEEK, corresponding to amino acid residues 270-283 of human P2X1 receptor
- 亚型
- IgG
- Top Product
- Discover our top product P2RX1 Primary Antibody
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anti-Purinergic Receptor P2X, Ligand Gated Ion Channel 1 (P2RX1) (AA 54-175) antibody
P2RX1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Purinergic Receptor P2X, Ligand Gated Ion Channel 1 (P2RX1) (AA 252-301) antibodyP2RX1 适用: 人, 犬, 猴, Cow, 马 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Purinergic Receptor P2X, Ligand Gated Ion Channel 1 (P2RX1) (Middle Region) antibodyP2RX1 适用: 人, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Purinergic Receptor P2X, Ligand Gated Ion Channel 1 (P2RX1) (AA 1-399) antibodyP2RX1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Purinergic Receptor P2X, Ligand Gated Ion Channel 1 (P2RX1) (Internal Region) antibodyP2RX1 适用: 人, 大鼠, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Purinergic Receptor P2X, Ligand Gated Ion Channel 1 (P2RX1) (Middle Region) antibodyP2RX1 适用: 人, 大鼠, 小鼠, 兔, 犬, Cow, 马, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Purinergic Receptor P2X, Ligand Gated Ion Channel 1 (P2RX1) (AA 382-399), (Intracellular) antibodyKO Validated P2RX1 适用: 大鼠 WB, IHC, FACS, IF, IC, IP 宿主: 兔 Polyclonal unconjugated
anti-Purinergic Receptor P2X, Ligand Gated Ion Channel 1 (P2RX1) (AA 270-283), (Extracellular) antibody (FITC)P2RX1 适用: 人 FACS, LCI 宿主: 兔 Polyclonal FITC
anti-Purinergic Receptor P2X, Ligand Gated Ion Channel 1 (P2RX1) (AA 270-283), (Extracellular) antibody (Atto 488)P2RX1 适用: 人 IHC, IF, LCI, IC 宿主: 兔 Polyclonal Atto 488
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- 应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: N/A
Application Dilutions Western blot wb: 1:200
- 说明
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Cited Application: IFC
Negative Control: (ABIN7236652)
Blocking Peptide: (ABIN7236652)
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Recosntitute with double distilled water (DDW) to a concentration of 1.0 mg/mL.
- 浓度
- 1 mg/mL
- 缓冲液
- PBS pH 7.4
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- 抗原
- P2RX1 (Purinergic Receptor P2X, Ligand Gated Ion Channel 1 (P2RX1))
- 别名
- P2RX1 (P2RX1 产品)
- 背景
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P2RX1, P2X purinoceptor 1,The P2X receptors belong to the ligand-gated ion channel family and are activated by extracellular ATP.The structure and function of the P2X receptors, investigated mainly using in vitro models, indicate their involvement in synaptic communication, cell death, and differentiation.Seven mammalian P2X receptor subtypes (P2X1-P2X7) have been identified and cloned1-3. All P2X receptor subtypes share the same structure of intracellular N- and C-termini two membrane-spanning domains and a large extracellular loop.All P2X receptor subtypes can assemble to form homomeric or heteromeric functional channels with the exception of P2X6, which only seems to function as part of a heteromeric complex4-9.The various P2X receptor subtypes show distinct expression patterns. P2X1-6 have been found in the central and peripheral nervous systems, while the P2X7 receptor is predominantly found in cells of the immune system4. The P2X1 receptor is present in smooth muscle, cerebellum, dorsal horn spinal neurons, and platelets where it is suggested to play a regulatory role during in vivo homeostasis and thrombosis3,4,10,11.
Alternative names: P2X1 Receptor, P2RX1, P2X purinoceptor 1 - 基因ID
- 5023
- NCBI登录号
- NM_002558
- UniProt
- P51575
- 途径
- Positive Regulation of Endopeptidase Activity
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