P2RX1 抗体 (Intracellular)
-
- 抗原 See all P2RX1 抗体
- P2RX1 (Purinergic Receptor P2X, Ligand Gated Ion Channel 1 (P2RX1))
-
抗原表位
- AA 382-399, Intracellular
-
适用
- 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This P2RX1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF), Immunochromatography (IC), Immunoprecipitation (IP)
- 原理
- A Rabbit Polyclonal Antibody to P2X1 Receptor
- 特异性
- Intracellular, C-terminus
- 交叉反应
- 人, 小鼠, 大鼠
- 预测反应
- 18 amino acid residues identical, human - 15,Mouse - 17
- 产品特性
- Anti-P2X1 Receptor Antibody is directed against an epitope of the rat P2X1 receptor. Anti-P2X1 Receptor Antibody (ABIN7043570, ABIN7045074 and ABIN7045075) can be used in western blot, immunoprecipitation, indirect flow cytometry, immunocytochemistry, and immunohistochemistry applications. It has been designed to recognize P2X1 receptor from rat, mouse, and human samples.
- 纯化方法
- Affinity purified on immobilized antigen.
- 质量等级
- KO Validated
- 免疫原
-
Immunogen: Synthetic peptide
Immunogen Sequence: (CS)DPVATSSTLGLQENMRTS, corresponding to amino acid residues 382-399 of rat P2X1 receptor
- 亚型
- IgG
- Top Product
- Discover our top product P2RX1 Primary Antibody
-
-
- 应用备注
-
Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: N/A
Application Dilutions Western blot wb: 1:200
- 说明
-
Cited Application: IP|IHC|ICC|IFC
Negative Control: (ABIN7236648)
Blocking Peptide: (ABIN7236648)
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- 0.2 mL double distilled water (DDW).
- 浓度
- 1 mg/mL
- 缓冲液
- PBS pH 7.4
- 储存条件
- 4 °C,-20 °C
- 储存方法
-
Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
-
- 抗原
- P2RX1 (Purinergic Receptor P2X, Ligand Gated Ion Channel 1 (P2RX1))
- 别名
- P2RX1 (P2RX1 产品)
- 背景
-
P2RX1, P2X purinoceptor 1,The P2X receptors belong to the ligand-gated ion channel family and are activated by extracellular ATP.The structure and function of the P2X receptors, investigated mainly using in vitro models, indicate their involvement in synaptic communication, cell death, and differentiation.Seven mammalian P2X receptor subtypes (P2X1-P2X7) have been identified and cloned.1,2,3 All P2X receptor subtypes share the same structure of intracellular N and C-termini two membrane-spanning domains and a large extracellular loop.All P2X receptor subtypes can assemble to form homomeric or heteromeric functional channels with the exception of P2X6, which only seems to function as part of a heteromeric complex.4-9The various P2X receptor subtypes show distinct expression patterns. P2X1-6 have been found in the central and peripheral nervous system, while the P2X7 receptor is predominantly found in cells of the immune system.4 The P2X1 receptor is present in smooth muscle, cerebellum, dorsal horn spinal neurons, and platelets where it is suggested to play a regulatory role during in vivo homeostasis and thrombosis.3,4,10,11
Alternative names: P2X1 Receptor, P2RX1, P2X purinoceptor 1 - 基因ID
- 25505
- NCBI登录号
- NM_002558
- UniProt
- P47824
- 途径
- Positive Regulation of Endopeptidase Activity
-