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- 抗原 See all KCNH6 抗体
- KCNH6 (Potassium Voltage-Gated Channel, Subfamily H (Eag-Related), Member 6 (KCNH6))
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抗原表位
- AA 185-198, Intracellular
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This KCNH6 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- 原理
- A Rabbit Polyclonal Antibody to KV11.2 (ERG-2) Channel
- 特异性
- Intracellular, N-terminal domain
- 交叉反应
- 人, 小鼠, 大鼠
- 预测反应
- Rat,chicken - identical, mouse - 13,14 amino acid residues identical
- 产品特性
- Anti-KCNH6 (erg2) Antibody (ABIN7043549 and ABIN7045012) directed against a highly conserved epitope of the human KV11.2 channel. The antibody can be used to detect KV11.2 in rat samples using both western blotting and immunohistochemistry applications.
- 纯化方法
- Affinity purified on immobilized antigen.
- 免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: TLNFVEFNLEKHRS(C), corresponding to amino acid residues 185-198 of human KV11.2 (erg2)
- 亚型
- IgG
- Top Product
- Discover our top product KCNH6 Primary Antibody
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anti-Potassium Voltage-Gated Channel, Subfamily H (Eag-Related), Member 6 (KCNH6) antibody
KCNH6 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Potassium Voltage-Gated Channel, Subfamily H (Eag-Related), Member 6 (KCNH6) (AA 173-222) antibodyKCNH6 适用: 人, 大鼠, 小鼠, 犬, Cow, 马, 兔, 豚鼠, Pig, Bat, 小鸡, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Potassium Voltage-Gated Channel, Subfamily H (Eag-Related), Member 6 (KCNH6) antibodyKCNH6 适用: 人, 大鼠, 小鼠, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Potassium Voltage-Gated Channel, Subfamily H (Eag-Related), Member 6 (KCNH6) (C-Term) antibodyKCNH6 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Potassium Voltage-Gated Channel, Subfamily H (Eag-Related), Member 6 (KCNH6) (AA 628-677) antibodyKCNH6 适用: 人, 大鼠, 小鼠, 豚鼠, 斑马鱼, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Potassium Voltage-Gated Channel, Subfamily H (Eag-Related), Member 6 (KCNH6) (C-Term) antibodyKCNH6 适用: 人, 犬, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Potassium Voltage-Gated Channel, Subfamily H (Eag-Related), Member 6 (KCNH6) (AA 827-876) antibodyKCNH6 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Potassium Voltage-Gated Channel, Subfamily H (Eag-Related), Member 6 (KCNH6) (AA 70-220) antibodyKCNH6 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Potassium Voltage-Gated Channel, Subfamily H (Eag-Related), Member 6 (KCNH6) (N-Term) antibodyKCNH6 适用: 人, 大鼠, 小鼠, 犬, Cow, 马, 兔, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: N/A
Application Dilutions Western blot wb: 1:200
- 说明
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Negative Control: (ABIN7236581)
Blocking Peptide: (ABIN7236581)
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Recosntitute with double distilled water (DDW) to a concentration of 1.0 mg/mL.
- 浓度
- 1 mg/mL
- 缓冲液
- PBS pH 7.4
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- 抗原
- KCNH6 (Potassium Voltage-Gated Channel, Subfamily H (Eag-Related), Member 6 (KCNH6))
- 别名
- KCNH6 (KCNH6 产品)
- 背景
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KV11.2, Potassium voltage-gated channel subfamily H member 6, Ether-a-go-go-related channel 2, Eag-related protein 2, ERG-2, hERG2,KV11.2 (erg2) is a member of the ether-a-go-go (EAG) subfamily of voltage-dependent K+ channels. The erg subfamily includes the closely related proteins KV11.1 (erg1) and KV11.3 (erg3) that possess the signature structure of the voltage-dependent K+ channels: six membrane-spanning domains with intracellular N- and C-termini. As with all voltage-dependent K+ channels, the functional channel is a tetramer composed of four subunits. It has been suggested that the KV11 subfamily members can form functional heteromultimers within the subfamily.KV11.2 produces currents characterized by strong inward rectification with slow activation and very rapid inactivation kinetics, which closely resemble those produced by the much studied channel KV11.1.The expression of KV11.2 seems to be limited to the brain and the pituitary gland. The same is true for the KV11.3 protein, while KV11.1 is more widely expressed. From a pharmacological point of view, KV11.2 channels can be blocked by well characterized organic blockers such as the anti-arrhythmic drug E-4031. In addition, the peptide toxins Ergtoxin-1 and BeKm-1 block KV11.2 with different potencies.
Alternative names: KCNH6 (erg2), KV11.2, Potassium voltage-gated channel subfamily H member 6, Ether-a-go-go-related channel 2, Eag-related protein 2, ERG-2, hERG2 - 基因ID
- 81033
- NCBI登录号
- NM_030779
- UniProt
- Q9H252
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