KCNQ3 抗体 (Intracellular)
Quick Overview for KCNQ3 抗体 (Intracellular) (ABIN7043505)
抗原
See all KCNQ3 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 668-686, Intracellular
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原理
- A Rabbit Polyclonal Antibody to KCNQ3 (KV7.3) Channel
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特异性
- Intracellular, C-terminus
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交叉反应
- 小鼠, 大鼠
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预测反应
- Mouse - identical, human - 18,19 amino acid residues identical
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产品特性
- Anti-KCNQ3 Antibody (ABIN7043505, ABIN7044961 and ABIN7044962) is a highly specific antibody directed against an epitope of the rat KV7.3 channel. The antibody can be used in western blot, immunoprecipitation, immunohistochemistry, and immunocytochemistry applications. It has been designed to recognize KCNQ3 from rat, human, and mouse samples.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: AEGEKKEDNRYSDLKTIIC, corresponding to amino acid residues 668-686 of rat KCNQ3
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亚型
- IgG
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anti-Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 3 (KCNQ3) (AA 763-872) antibody
KCNQ3 适用: 人 ELISA, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 3 (KCNQ3) (AA 580-629) antibodyKCNQ3 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 3 (KCNQ3) (Middle Region) antibodyKCNQ3 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:200
Application Dilutions Western blot wb: 1:200
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说明
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Cited Application: IP
Negative Control: (ABIN7236449)
Blocking Peptide: (ABIN7236449)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 0.2 mL double distilled water (DDW).
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4
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储存条件
- 4 °C,-20 °C
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储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- KCNQ3 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 3 (KCNQ3))
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别名
- KCNQ3
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背景
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KV7.3, Potassium voltage-gated channel subfamily KQT member 3, BFNC2,The KCNQ family of voltage-gated K+ channels includes 5 known members: KCNQ1 to KCNQ5. Structurally, the KCNQ family belongs to the six transmembrane domain category of K+ channels. KCNQ family members can form either homomultimeric or heteromultimeric channels with different functional consequences. For example KCNQ2 and KCNQ3 heteromultimers give rise to a much larger channel current than when either protein is expressed alone, probably due to enhanced plasma membrane expression of the combined channel. Indeed, KCNQ2/KCNQ3 heteromultimers are believed to be the molecular correlates of the so-called M current. This current is a K+ neuronal current that is strongly inhibited by the activation of the M1 subtype of the muscarinic acetylcholine receptor. Mutations in either KCNQ2 or KCNQ3 are associated with a form of epilepsy known as benign familial neonatal convulsions (BFNC).
Alternative names: KCNQ3, KV7.3, Potassium voltage-gated channel subfamily KQT member 3, BFNC2 -
基因ID
- 29682
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NCBI登录号
- NM_004519
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UniProt
- O88944
抗原
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