KCNJ10 抗体 (Intracellular)
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- 抗原 See all KCNJ10 抗体
- KCNJ10 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 10 (KCNJ10))
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抗原表位
- AA 356-375, Intracellular
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适用
- 大鼠
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宿主
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豚鼠
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克隆类型
- 多克隆
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标记
- This KCNJ10 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunochromatography (IC)
- 原理
- A Guinea Pig Polyclonal Antibody to Kir4.1 (KCNJ10) Channel
- 特异性
- Intracellular, C-terminus
- 交叉反应
- 人, 小鼠, 大鼠
- 预测反应
- Human,mouse - identical
- 产品特性
- Guinea pig Anti-Kir4.1 (KCNJ10) Antibody is a highly specific antibody directed against an epitope of the rat protein. The antibody can be used in western blot, immunohistochemistry, and immunocytochemistry applications. It has been designed to recognize Kir4.1 potassium channel from human, rat, and mouse samples. The antigen used to immunize guinea pigs is the same as Anti-Kir4.1 (KCNJ10) Antibody (ABIN7043469, ABIN7044943 and ABIN7044944) raised in rabbit. Our line of guinea pig antibodies enables more flexibility with our products such as multiplex staining studies, immunoprecipitation, etc.
- 纯化方法
- Affinity purified on immobilized antigen.
- 质量等级
- KO Validated
- 免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: (C)KLEESLREQAEKEGSALSVR, corresponding to amino acid residues 356-375 of rat Kir4.1
- 亚型
- IgG
- Top Product
- Discover our top product KCNJ10 Primary Antibody
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anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 10 (KCNJ10) (AA 276-379) antibody
KCNJ10 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1C11 unconjugated
anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 10 (KCNJ10) antibodyKCNJ10 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 10 (KCNJ10) antibody (HRP)KCNJ10 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal HRP
anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 10 (KCNJ10) antibody (FITC)KCNJ10 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal FITC
anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 10 (KCNJ10) antibody (Atto 594)KCNJ10 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal Atto 594
anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 10 (KCNJ10) antibody (Biotin)KCNJ10 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal Biotin
anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 10 (KCNJ10) antibody (PE)KCNJ10 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal PE
anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 10 (KCNJ10) antibody (APC)KCNJ10 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal APC
anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 10 (KCNJ10) antibody (PerCP)KCNJ10 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal PerCP
anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 10 (KCNJ10) antibody (Atto 488)KCNJ10 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal Atto 488
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- 应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:300
Application Dilutions Western blot wb: 1:800
- 说明
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Negative Control: (ABIN7236361)
Blocking Peptide: (ABIN7236361)
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- 0.2 mL double distilled water (DDW).
- 浓度
- 1 mg/mL
- 缓冲液
- PBS pH 7.4
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- 抗原
- KCNJ10 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 10 (KCNJ10))
- 别名
- KCNJ10 (KCNJ10 产品)
- 背景
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ATP-sensitive inward rectifier potassium channel 10, KAB-2, BIR10, BIRK1, Kir1.2, Potassium channel inwardly rectifying subfamily J member 10,Kir4.1 is a member of the family of inward rectifying K+ channels. The family includes 15 members that are structurally and functionally different from the voltage-dependent K+ channels.The family's topology consists of two transmembrane domains that flank a single and highly conserved pore region with intracellular N- and C-termini. As is the case for the voltage-dependent K+ channels the functional unit for the Kir channels is composed of four subunits that can assemble as either homo or heteromers.Kir channels are characterized by a K+ efflux that is limited by depolarizing membrane potentials thus making them essential for controlling resting membrane potential and K+ homeostasis.Kir4.1 is a member of the Kir4 subfamily that includes one other member: Kir4.2. Kir4.1 can co-assemble with Kir4.2 but also with other Kir channels such as Kir2.1 and Kir5.1.The Kir4 subfamily has been classified as weak rectifiers with intermediate conductance. Kir4.1, encoded by KCNJ10, is mainly expressed in brain, specifically in glia cells, but also in retina, ear and kidney1,2.It has been proposed that Kir4.1 has an essential role in glial K+ buffering, a process that re-uptakes the K+ released during neuronal activity into the intracellular interstitial space. Loss of Kir4.1 causes retinal defects and loss of endochoclear potential3.
Alternative names: Kir4.1, ATP-sensitive inward rectifier potassium channel 10, KAB-2, BIR10, BIRK1, Kir1.2, Potassium channel Inwardly rectifying subfamily J member 10 - 基因ID
- 29718
- NCBI登录号
- NM_002241
- UniProt
- P49655
- 途径
- Dicarboxylic Acid Transport, Regulation of long-term Neuronal Synaptic Plasticity
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