KCNK1 抗体 (Extracellular, P1 Loop)
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Quick Overview for KCNK1 抗体 (Extracellular, P1 Loop) (ABIN7043443)
抗原
See all KCNK1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 53-69, Extracellular, P1 Loop
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原理
- A Rabbit Polyclonal Antibody to KCNK1 Channel
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Rat,mouse,pig - identical
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产品特性
- Anti-KCNK1 (extracellular) Antibody is directed against an epitope of the human K2P1.1 channel. Anti-KCNK1 (extracellular) Antibody (ABIN7043443, ABIN7045008 and ABIN7045009) can be used in western blot and immunohistochemistry applications. The antibody recognizes an extracellular epitope and is thus ideal for detecting KCNK1 in living cells. It has been designed to recognize KCNK1 from mouse, rat and human samples.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
- RQELRKLKRRFLEEHEC, corresponding to amino acid residues 53-69 of human KCNK1
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亚型
- IgG
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anti-Potassium Channel Subfamily K Member 1 (KCNK1) (AA 268-336) antibody
KCNK1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Potassium Channel Subfamily K Member 1 (KCNK1) (N-Term) antibodyKCNK1 适用: 人, 大鼠, 小鼠 ELISA, WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Potassium Channel Subfamily K Member 1 (KCNK1) (AA 293-320), (C-Term) antibodyKCNK1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB32239 unconjugated
anti-Potassium Channel Subfamily K Member 1 (KCNK1) (AA 265-336) antibodyKCNK1 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 4D7 unconjugated
anti-Potassium Channel Subfamily K Member 1 (KCNK1) (C-Term) antibodyKCNK1 适用: 人, 小鼠, 兔, 马, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Potassium Channel Subfamily K Member 1 (KCNK1) (AA 300-328), (C-Term) antibodyKCNK1 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB: 1:200-1:300
FC: The optimal concentration should be determined by the user
ICC: The optimal concentration should be determined by the user
IHC: The optimal concentration should be determined by the user
IP: The optimal concentration should be determined by the user
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说明
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Negative Control: (ABIN7236284)
Blocking Peptide: (ABIN7236284)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.
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浓度
- 0.8 mg/mL
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缓冲液
- PBS pH 7.4, 1 % BSA with 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
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- KCNK1 (Potassium Channel Subfamily K Member 1 (KCNK1))
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别名
- KCNK1
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背景
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Synonyms: Potassium channel subfamily K member 1, Inward rectifying K+ channel protein TWIK-1, K2P1.1, HOHO1, KCNO1
Description: KCNK1 (also named TWIK-1 or K2P1.1) is a member of the 2-pore (2P) domain K+ channels family that, currently, includes 16 members. These channels show little time- or voltage-dependence and are considered to be "leak" or "background" K+ channels, thereby generating background currents which help set the membrane resting potential and cell excitation. The K2P channels have a signature topology that includes four transmembrane domains and two pore domains with intracellular N- and C termini. K2P channels are regulated by diverse physical and chemical stimuli including temperature, pH , mechanical stretch, inhalation anesthetics, etc. but are insensitive to the classical K+ channel blockers.KCNK1 was the first of the K2P channels to be identified and as its original name indicates (Tandem of P domains in a Weak Inward rectifier K+ channel) the channel behaves as a weak inward rectifier when expressed in heterologous systems. The channel is ubiquitously expressed with the most prominent expression in the brain, kidney and heart.
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基因ID
- 3775
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NCBI登录号
- NM_002245
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UniProt
- O00180
抗原
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