Neurotrophin 4 抗体 (Intracellular)
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Quick Overview for Neurotrophin 4 抗体 (Intracellular) (ABIN7043393)
抗原
See all Neurotrophin 4 (NTF4) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 43-52, AA 123-132, Intracellular
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原理
- A Rabbit Polyclonal Antibody to Neurotrophin 4
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Rat - identical
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产品特性
- Anti-Neurotrophin 4 Antibody is directed against an epitope of human Neurotrophin 4. Anti-Neurotrophin 4 Antibody (ABIN7043393 and ABIN7044750) can be used in western blot and immunohistochemistry applications. It has been designed to recognize from rat, mouse and human samples.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
- LGEVPAAGGSPL(C), corresponding to amino acid residues 43-52 of mature human NT-4 (residues 123-132 of the precursor NT-4)
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亚型
- IgG
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anti-Neurotrophin 4 (NTF4) (AA 25-210) antibody
NTF4 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Neurotrophin 4 (NTF4) (AA 80-209) antibodyNTF4 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Neurotrophin 4 (NTF4) (AA 121-210) antibodyNTF4 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Neurotrophin 4 (NTF4) (AA 1-210) antibodyNTF4 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Neurotrophin 4 (NTF4) (AA 1-210) antibodyNTF4 适用: 人 ELISA, PLA 宿主: 小鼠 Monoclonal 1G12 unconjugated
anti-Neurotrophin 4 (NTF4) (AA 82-210) antibodyNTF4 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Neurotrophin 4 (NTF4) (AA 81-210) antibodyNTF4 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Neurotrophin 4 (NTF4) (AA 81-210) antibodyNTF4 适用: 人 WB, IHC, IF 宿主: 小鼠 Monoclonal 2E8 unconjugated
anti-Neurotrophin 4 (NTF4) (N-Term) antibodyNTF4 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Neurotrophin 4 (NTF4) (Internal Region) antibodyVerified NTF4 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
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应用备注
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WB: 1:200
FC: The optimal concentration should be determined by the user
ICC: The optimal concentration should be determined by the user
IHC: The optimal concentration should be determined by the user
IP: The optimal concentration should be determined by the user
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说明
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Cited Application: IFC
Negative Control: (ABIN7566010)
Blocking Peptide: (ABIN7566010)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.
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浓度
- 0.8 mg/mL
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缓冲液
- PBS pH 7.4, 1 % BSA with 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
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- Neurotrophin 4 (NTF4)
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别名
- NTF4
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背景
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Synonyms: NTF4, Neutrophic factor 4, Neurotrophin 5, NT-5, NTF5, Neutrophic factor 5, NT 4/5
Description: The neurotrophins ("neuro" meaning nerve and "trophe" meaning nutrient) are a family of soluble, basic growth factors which regulate neuronal development, maintenance, survival and death in the CNS and PNS.1 Neurotrophin-4 (NT-4) is expressed in neurons of the superior cervical, stellate and celiac ganglion,2 T-cells3 and is synthesized by keratinocytes.4 The structural hallmark of all neurotrophins is the characteristic arrangement of the disulfide bridges, known as the cysteine knot, which has been found in other growth factors such as PDGF.5 The rat and human forms of NT-4 are 96 % homologous. NT-4 has been shown to promote dendritic outgrowth and calcium currents in cultured mesencephalic dopamine neurons,6 to promote growth and remodeling of adult motor neuron innervation,7 to be anterograde survival factors for postsynaptic cells8 and to protect against apoptotic neuronal death.9 The biological effects of NT-4 are mediated by two receptors: TrkB, which is specific for NT-4 and BDNF, and p75NTR, which binds all the neurotrophins.10
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基因ID
- 16485
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NCBI登录号
- NM_006179
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UniProt
- P34130
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途径
- RTK signaling
抗原
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