Neurotrophin 4 抗体 (Intracellular)
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- 抗原 See all Neurotrophin 4 (NTF4) 抗体
- Neurotrophin 4 (NTF4)
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抗原表位
- AA 43-52, AA 123-132, Intracellular
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Neurotrophin 4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- 原理
- A Rabbit Polyclonal Antibody to Neurotrophin 4
- 特异性
- Intracellular
- 交叉反应
- 人, 小鼠, 大鼠
- 预测反应
- Rat - identical
- 产品特性
- Anti-Neurotrophin 4 Antibody is directed against an epitope of human Neurotrophin 4. Anti-Neurotrophin 4 Antibody (ABIN7043393 and ABIN7044750) can be used in western blot and immunohistochemistry applications. It has been designed to recognize from rat, mouse and human samples.
- 纯化方法
- Affinity purified on immobilized antigen.
- 免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: LGEVPAAGGSPL(C), corresponding to amino acid residues 43-52 of mature human NT-4 (residues 123-132 of the precursor NT-4)
- 亚型
- IgG
- Top Product
- Discover our top product NTF4 Primary Antibody
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anti-Neurotrophin 4 (NTF4) (AA 25-210) antibody
NTF4 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Neurotrophin 4 (NTF4) (AA 80-209) antibodyNTF4 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Neurotrophin 4 (NTF4) (AA 121-210) antibodyNTF4 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Neurotrophin 4 (NTF4) (AA 82-210) antibodyNTF4 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Neurotrophin 4 (NTF4) (AA 1-210) antibodyNTF4 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Neurotrophin 4 (NTF4) (AA 1-210) antibodyNTF4 适用: 人 ELISA, PLA 宿主: 小鼠 Monoclonal 1G12 unconjugated
anti-Neurotrophin 4 (NTF4) (AA 81-210) antibodyNTF4 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Neurotrophin 4 (NTF4) (AA 81-210) antibodyNTF4 适用: 人 WB, IHC, IF 宿主: 小鼠 Monoclonal 2E8 unconjugated
anti-Neurotrophin 4 (NTF4) (Internal Region) antibodyVerified NTF4 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Neurotrophin 4 (NTF4) (AA 35-84) antibodyNTF4 适用: 人, 小鼠, 犬, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: N/A
Application Dilutions Western blot wb: 1:200
- 说明
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Cited Application: IFC
Negative Control: (ABIN7566010)
Blocking Peptide: (ABIN7566010)
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Recosntitute with double distilled water (DDW) to a concentration of 1.0 mg/mL.
- 浓度
- 1 mg/mL
- 缓冲液
- PBS pH 7.4
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- 抗原
- Neurotrophin 4 (NTF4)
- 别名
- NTF4 (NTF4 产品)
- 背景
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NTF4, Neutrophic factor 4, Neurotrophin 5, NT-5, NTF5, Neutrophic factor 5, NT 4/5,The neurotrophins ("neuro" meaning nerve and "trophe" meaning nutrient) are a family of soluble, basic growth factors which regulate neuronal development, maintenance, survival and death in the CNS and PNS.1 Neurotrophin-4 (NT-4) is expressed in neurons of the superior cervical, stellate and celiac ganglion,2 T-cells3 and is synthesized by keratinocytes.4 The structural hallmark of all neurotrophins is the characteristic arrangement of the disulfide bridges, known as the cysteine knot, which has been found in other growth factors such as PDGF.5 The rat and human forms of NT-4 are 96 % homologous. NT-4 has been shown to promote dendritic outgrowth and calcium currents in cultured mesencephalic dopamine neurons,6 to promote growth and remodeling of adult motor neuron innervation,7 to be anterograde survival factors for postsynaptic cells8 and to protect against apoptotic neuronal death.9 The biological effects of NT-4 are mediated by two receptors: TrkB, which is specific for NT-4 and BDNF, and p75NTR, which binds all the neurotrophins.10
Alternative names: Neurotrophin 4 (NT-4), NTF4, Neutrophic factor 4, Neurotrophin 5, NT-5, NTF5, Neutrophic factor 5, NT 4/5 - 基因ID
- 16485
- NCBI登录号
- NM_006179
- UniProt
- P34130
- 途径
- RTK signaling
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