Neurotrophin 3 抗体 (Intracellular)
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Quick Overview for Neurotrophin 3 抗体 (Intracellular) (ABIN7886722)
抗原
See all Neurotrophin 3 (NTF3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 39-48, AA 177-186, Intracellular
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原理
- A Rabbit Polyclonal Antibody to Neurotrophin 3
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Rat,mouse,chicken,Xenopus - identical, cat - 9,10 amino acid residues identical
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产品特性
- Anti-Neurotrophin 3 Antibody is directed against an epitope of human Neurotrophin 3. Anti-Neurotrophin 3 Antibody (ABIN7043392, ABIN7044748 and ABIN7044749) can be used in western blot and immunohistochemical applications. It has been designed to recognize from rat, mouse and human samples.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
- GEIKTGNSPV(C), corresponding to amino acid residues 39-48 of mature human NT-3 (residues 177-186 of the NT-3 precursor)
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亚型
- IgG
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anti-Neurotrophin 3 (NTF3) (AA 139-257) antibody
NTF3 适用: 人 WB, IHC, ICC, IHC (p), IF 宿主: 小鼠 Monoclonal 5A2 unconjugated
anti-Neurotrophin 3 (NTF3) (AA 152-184), (C-Term) antibodyNTF3 适用: 人, 小鼠, 大鼠 WB, FACS 宿主: 兔 Polyclonal RB14406 unconjugated
anti-Neurotrophin 3 (NTF3) (AA 19-100) antibodyNTF3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Neurotrophin 3 (NTF3) (AA 19-257) antibodyNTF3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Neurotrophin 3 (NTF3) (AA 130-255) antibodyNTF3 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal unconjugated
anti-Neurotrophin 3 (NTF3) (AA 1-257) antibodyNTF3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Neurotrophin 3 (NTF3) (N-Term) antibodyNTF3 适用: 人, 小鼠, 大鼠, Cow, 犬, Hamster, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Neurotrophin 3 (NTF3) (AA 130-255) antibodyNTF3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Neurotrophin 3 (NTF3) (AA 122-151) antibodyNTF3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB14463 unconjugated
anti-Neurotrophin 3 (NTF3) (AA 174-189), (Middle Region) antibodyNTF3 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB: 1:200
FC: The optimal concentration should be determined by the user
ICC: The optimal concentration should be determined by the user
IHC: 1:300
IP: The optimal concentration should be determined by the user
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说明
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Cited Application: IP|IHC
Negative Control: (ABIN7236144)
Blocking Peptide: (ABIN7236144)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 25 μL, 50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.
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浓度
- 0.8 mg/mL
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缓冲液
- PBS pH 7.4, 1 % BSA with 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
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- Neurotrophin 3 (NTF3)
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别名
- NTF3
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背景
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Synonyms: NTF3, Nerve growth factor 2, NGF2, HDNF
Description: The neurotrophins ("neuro" meaning nerve and "trophe" meaning nutrient) are a family of soluble, basic growth factors which regulate neuronal development, maintenance, survival and death in the CNS and PNS.1 The structural hallmark of all neurotrophins is the characteristic arrangement of the disulfide bridges, known as the cysteine knot, which has been found in other growth factors such as PDGF.2 The rat and human forms of neurotrophin-3 (NT-3) are 96 % homologous. NT-3 has been shown to strengthen synaptic connections to motoneurons in the neonatal rat,3 to serve as an anti-inflammatory factor, to suppress microglial activation,4 to play a critical role in regulating T helper 1/T helper 2 cell balance5 and to modify potassium currents in isolated inner hair cells from guinea pig cochlea.6 The biological effects of NT-3 are mediated by two receptors: TrkC, which is specific for NT-3, and p75NTR, which binds all the neurotrophins.7
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基因ID
- 4908
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NCBI登录号
- NM_001102654
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UniProt
- P20783
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途径
- RTK signaling, Neurotrophin Signaling Pathway
抗原
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