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KISS1R 抗体 (Extracellular)

KISS1R 适用: 人 WB, IHC, IF, IF (cc), LCI 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7043294
发货至: 中国
  • 抗原 See all KISS1R 抗体
    KISS1R (KISS1 Receptor (KISS1R))
    抗原表位
    • 12
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 292-305, Extracellular
    适用
    • 40
    • 28
    • 20
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 45
    • 1
    克隆类型
    • 45
    • 1
    多克隆
    标记
    • 22
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KISS1R antibody is un-conjugated
    应用范围
    • 23
    • 13
    • 12
    • 8
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunofluorescence (Cultured Cells) (IF (cc)), Live Cell Imaging (LCI)
    原理
    A Rabbit Polyclonal Antibody to Kisspeptin Receptor
    特异性
    3rd extracellular loop
    交叉反应
    人, 大鼠
    预测反应
    mouse - 12,14 amino acid residues identical,Rat - 13
    产品特性
    Anti-KISS1 Receptor (GPR54) (extracellular) Antibody (ABIN7043294, ABIN7044548 and ABIN7044549)) is a highly specific antibody directed against an epitope of the human kisspeptin receptor. The antibody can be used in western blot and immunohistochemistry applications. It has been designed to recognize KISS1R from human, rat, and mouse samples.
    纯化方法
    Affinity purified on immobilized antigen.
    免疫原

    Immunogen: Synthetic peptide

    Immunogen Sequence: (C)GSWHPRSYAAYALK, corresponding to amino acid residues 292-305 of human KISS1R

    亚型
    IgG
    Top Product
    Discover our top product KISS1R Primary Antibody
  • 应用备注

    Antigen preadsorption control: 1 μg peptide per 1 μg antibody

    Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:100

    Application Dilutions Western blot wb: 1:500

    说明

    Cited Application: IHC|ICC

    Negative Control: BLP-KR001

    Blocking Peptide: BLP-KR001

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    0.2 mL double distilled water (DDW).
    浓度
    1 mg/mL
    缓冲液
    PBS pH 7.4
    储存条件
    4 °C,-20 °C
    储存方法

    Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.

    Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

  • 抗原
    KISS1R (KISS1 Receptor (KISS1R))
    别名
    KISS1R (KISS1R 产品)
    背景
    Kisspeptin receptor, KISS1R, Metastin receptor, AXOR12,The kisspeptin receptor (KISS1R, GPCR54) is a member of the G-protein coupled receptor superfamily. KISS1R natural ligands are peptides called kisspeptins which are encoded by the Kiss1 gene. The Kiss1 gene was originally discovered by Hershey scientists who named it after their famous chocolate, the "Kiss".The kisspeptins, acting through KISS1R, were found to be potent inhibitors of metastasis in a variety of cancer cell types including thyroid and pancreatic cancer cells. KISS1R and kisspeptins are involved in the direct regulation of the reproductive neuroendocrine axis.KISS1R is widely distributed throughout the brain, where it is most highly expressed in the hypothalamic and amygdaloid nuclei. High expression was also found in the pancreas and placenta. Lower-level expression was found in a variety of other peripheral tissues including peripheral blood leukocytes, kidney, lung, testes, spleen, thymus, adrenal glands and lymph nodes.1-3

    Alternative names: KISS1 Receptor (GPR54), Kisspeptin receptor, KISS1R, Metastin receptor, AXOR12
    基因ID
    84634
    NCBI登录号
    NM_032551
    UniProt
    Q969F8
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