KISS1R 抗体 (Extracellular)
Quick Overview for KISS1R 抗体 (Extracellular) (ABIN7043294)
抗原
See all KISS1R 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 292-305, Extracellular
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原理
- A Rabbit Polyclonal Antibody to Kisspeptin Receptor
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特异性
- 3rd extracellular loop
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交叉反应
- 人, 大鼠
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预测反应
- mouse - 12,14 amino acid residues identical,Rat - 13
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产品特性
- Anti-KISS1 Receptor (GPR54) (extracellular) Antibody (ABIN7043294, ABIN7044548 and ABIN7044549) is a highly specific antibody directed against an epitope of the human kisspeptin receptor. The antibody can be used in western blot and immunohistochemistry applications. It has been designed to recognize KISS1R from human, rat, and mouse samples.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: (C)GSWHPRSYAAYALK, corresponding to amino acid residues 292-305 of human KISS1R
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亚型
- IgG
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anti-KISS1 Receptor (KISS1R) (Extracellular Domain) antibody
KISS1R 适用: 人, 小鼠, 大鼠, Cow, Pig, Bat, 犬, Hamster, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-KISS1 Receptor (KISS1R) (C-Term) antibodyKISS1R 适用: 人 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-KISS1 Receptor (KISS1R) (AA 121-200) antibodyKISS1R 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-KISS1 Receptor (KISS1R) (C-Term) antibodyKISS1R 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-KISS1 Receptor (KISS1R) (N-Term) antibodyKISS1R 适用: 人 IHC, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated
anti-KISS1 Receptor (KISS1R) (Cytoplasmic Domain) antibodyKISS1R 适用: 人, Cow, Pig, 山羊 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-KISS1 Receptor (KISS1R) (AA 309-372) antibodyKISS1R 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-KISS1 Receptor (KISS1R) (AA 235-263) antibodyKISS1R 适用: 人 WB 宿主: 兔 Polyclonal RB40407 unconjugated
anti-KISS1 Receptor (KISS1R) (2nd Extracellular Domain) antibodyKISS1R 适用: 人 IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:100
Application Dilutions Western blot wb: 1:500
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说明
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Cited Application: IHC|ICC
Negative Control: (ABIN7235833)
Blocking Peptide: (ABIN7235833)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 0.2 mL double distilled water (DDW).
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4
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储存条件
- 4 °C,-20 °C
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储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- KISS1R (KISS1 Receptor (KISS1R))
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别名
- KISS1R
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背景
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Kisspeptin receptor, KISS1R, Metastin receptor, AXOR12,The kisspeptin receptor (KISS1R, GPCR54) is a member of the G-protein coupled receptor superfamily. KISS1R natural ligands are peptides called kisspeptins which are encoded by the Kiss1 gene. The Kiss1 gene was originally discovered by Hershey scientists who named it after their famous chocolate, the "Kiss".The kisspeptins, acting through KISS1R, were found to be potent inhibitors of metastasis in a variety of cancer cell types including thyroid and pancreatic cancer cells. KISS1R and kisspeptins are involved in the direct regulation of the reproductive neuroendocrine axis.KISS1R is widely distributed throughout the brain, where it is most highly expressed in the hypothalamic and amygdaloid nuclei. High expression was also found in the pancreas and placenta. Lower-level expression was found in a variety of other peripheral tissues including peripheral blood leukocytes, kidney, lung, testes, spleen, thymus, adrenal glands and lymph nodes.1-3
Alternative names: KISS1 Receptor (GPR54), Kisspeptin receptor, KISS1R, Metastin receptor, AXOR12 -
基因ID
- 84634
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NCBI登录号
- NM_032551
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UniProt
- Q969F8
抗原
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