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Metabotropic Glutamate Receptor 6 抗体 (Extracellular)

Name: Metabotropic Glutamate Receptor 6 抗体 (Extracellular)
SKU: ABIN7043254
Availability: OutOfStock

This anti-Metabotropic Glutamate Receptor 6 antibody is a 兔多克隆 antibody detecting Metabotropic Glutamate Receptor 6 in WB. Suitable for 大鼠.

Western blot analysis of rat eye lysates: - 1. (Metabotropic Glutamate Receptor 6 抗体 (Extracellular))

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产品编号 ABIN7043254

发货至: 中国

Quick Overview for Metabotropic Glutamate Receptor 6 抗体 (Extracellular) (ABIN7043254)

抗原

See all Metabotropic Glutamate Receptor 6 (GRM6) 抗体

Metabotropic Glutamate Receptor 6 (GRM6) (Glutamate Receptor, Metabotropic 6 (GRM6))

适用

大鼠

宿主

兔

克隆类型

多克隆

标记

This Metabotropic Glutamate Receptor 6 antibody is un-conjugated

应用范围

Western Blotting (WB)

Discover our top product GRM6 Primary Antibody

抗原表位
12

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1

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1
AA 368-381, Extracellular

原理

A Rabbit Polyclonal Antibody to Metabotropic Glutamate Receptor 6

特异性

Extracellular, N-terminus

交叉反应

人, 小鼠, 大鼠

预测反应

14 amino acid residues identical,Mouse, human - 12,rat - 13

产品特性

Anti-mGluR6 (extracellular) Antibody (ABIN7043254, ABIN7044361 and ABIN7044362) is a highly specific antibody directed against an epitope of the rat protein. The antibody can be used in western blot analysis. The antibody recognizes an extracellular epitope and can potentially detect the receptor in living cells. It has been designed to recognize mGluR6 from rat, mouse, and human samples.

纯化方法

Affinity purified on immobilized antigen.

免疫原

Immunogen: Synthetic peptide
Immunogen Sequence: (C)GQSDDSTRK(S)TGEE, corresponding to amino acid residues 368-381 of rat mGluR6

亚型

IgG
anti-Glutamate Receptor, Metabotropic 6 (GRM6) (AA 828-877) antibody
GRM6 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Glutamate Receptor, Metabotropic 6 (GRM6) (C-Term) antibody
GRM6 适用: 人, 大鼠, 小鼠 WB, IF, IC 宿主: 兔 Polyclonal unconjugated

anti-Glutamate Receptor, Metabotropic 6 (GRM6) (AA 480-585) antibody
GRM6 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 7D9C9 unconjugated

anti-Glutamate Receptor, Metabotropic 6 (GRM6) (C-Term) antibody
GRM6 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Glutamate Receptor, Metabotropic 6 (GRM6) (C-Term) antibody
GRM6 适用: 人, 大鼠, 小鼠, 犬, 兔, Cow, 豚鼠, 马, 斑马鱼, Saccharomyces cerevisiae WB 宿主: 兔 Polyclonal unconjugated

anti-Glutamate Receptor, Metabotropic 6 (GRM6) (AA 477-566) antibody
GRM6 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1A11 unconjugated

anti-Glutamate Receptor, Metabotropic 6 (GRM6) (AA 700-749) antibody
GRM6 适用: 人, 大鼠, 小鼠, 犬, 兔, Cow, 豚鼠, 马, 猴, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Glutamate Receptor, Metabotropic 6 (GRM6) (N-Term) antibody
GRM6 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Glutamate Receptor, Metabotropic 6 (GRM6) antibody
GRM6 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Glutamate Receptor, Metabotropic 6 (GRM6) (AA 370-531) antibody
GRM6 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated

应用备注

Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: N/A
Application Dilutions Western blot wb: 1:200

说明

Cited Application: IHC
Negative Control: (ABIN7235701)
Blocking Peptide: (ABIN7235701)

限制

仅限研究用
状态

Lyophilized

溶解方式

Recosntitute with double distilled water (DDW) to a concentration of 1.0 mg/mL.

浓度

1 mg/mL

缓冲液

PBS pH 7.4

储存条件

4 °C,-20 °C

储存方法

Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
抗原

Metabotropic Glutamate Receptor 6 (GRM6) (Glutamate Receptor, Metabotropic 6 (GRM6))

别名

GRM6

背景

Metabotropic glutamate receptor 6, GRM6, mGlu6, Gprc1f,Glutamate is the principal excitatory neurotransmitter in the central nervous system. It operates through two main classes of receptors: ionotropic receptors (iGluRs), which are ligand-gated ion channels, and metabotropic receptors (mGluRs), which couple to G-proteins to modulate cellular responses via ion channels or intracellular second messengers.The metabotropic receptors include eight family members (mGluR1-mGluR8) classified into three groups according to their sequence similarities, signal transduction, and agonist selectivity. They all share a common structure, being composed of a single polypeptide with large N-terminal extracellular domain connected through a seven transmembrane domain motif to the intracellular C-terminal tail1,2. The different mGluR subtypes are localized at both presynaptic and postsynaptic membranes, and are involved in the generation of slow excitatory and inhibitory synaptic potentials, modulation of synaptic transmission, synaptic integration, and plasticity3.mGluR6 belongs to the third group of metabotrophic glutamate receptors. Its expression in the central nervous system is restricted to retinal rod bipolar cells, and it's localized to their postsynaptic dendritic membranes3,4. In the peripheral nervous system, it is also detected in bone marrow stromal cells6. mGluR6 inhibits adenylate cyclase, and was shown to inhibit Ca2+ influx and nitric oxide synthase activity3,5,6.

Alternative names: mGluR6, Metabotropic glutamate receptor 6, GRM6, mGlu6, Gprc1f

基因ID

24419

NCBI登录号

NM_000843

UniProt

P35349