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Metabotropic Glutamate Receptor 6 抗体

GRM6 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1944817
发货至: 中国
  • 抗原 See all Metabotropic Glutamate Receptor 6 (GRM6) 抗体
    Metabotropic Glutamate Receptor 6 (GRM6) (Glutamate Receptor, Metabotropic 6 (GRM6))
    适用
    • 47
    • 17
    • 16
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 46
    • 3
    克隆类型
    • 47
    • 2
    多克隆
    标记
    • 26
    • 4
    • 4
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    • 3
    • 3
    • 1
    • 1
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    This Metabotropic Glutamate Receptor 6 antibody is un-conjugated
    应用范围
    • 35
    • 25
    • 12
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    亚型
    IgG1
    Top Product
    Discover our top product GRM6 Primary Antibody
  • 应用备注
    WB: 1:1000. IHC: 1:50-1:100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    储存条件
    4 °C,-20 °C
  • Devi, Markandeya, Maddodi, Dhingra, Vardi, Balijepalli, Setaluri: "Metabotropic glutamate receptor 6 signaling enhances TRPM1 calcium channel function and increases melanin content in human melanocytes." in: Pigment cell & melanoma research, Vol. 26, Issue 3, pp. 348-56, (2013) (PubMed).

    Dryja, McGee, Berson, Fishman, Sandberg, Alexander, Derlacki, Rajagopalan: "Night blindness and abnormal cone electroretinogram ON responses in patients with mutations in the GRM6 gene encoding mGluR6." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 13, pp. 4884-9, (2005) (PubMed).

    Hashimoto, Inazawa, Okamoto, Tagawa, Bessho, Honda, Nakanishi: "The whole nucleotide sequence and chromosomal localization of the gene for human metabotropic glutamate receptor subtype 6." in: The European journal of neuroscience, Vol. 9, Issue 6, pp. 1226-35, (1997) (PubMed).

  • 抗原
    Metabotropic Glutamate Receptor 6 (GRM6) (Glutamate Receptor, Metabotropic 6 (GRM6))
    别名
    mGluR6 (GRM6 产品)
    别名
    mGluR6 antibody, CSNB1B antibody, GPRC1F antibody, MGLUR6 antibody, mGlu6 antibody, GRM6 antibody, BC021919 antibody, Gm3 antibody, Gprc1f antibody, nerg1 antibody, nob2 antibody, nob3 antibody, nob4 antibody, si:dkey-52h10.3 antibody, cb496 antibody, grma antibody, zK13A21.16 antibody, zgc:158329 antibody, glutamate metabotropic receptor 6 antibody, glutamate receptor, metabotropic 6 antibody, glutamate receptor, metabotropic 6a antibody, glutamate receptor, metabotropic 6b antibody, Grm6 antibody, GRM6 antibody, grm6a antibody, grm6b antibody
    背景
    G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity (By similarity). Signaling stimulates TRPM1 channel activity and Ca(2+) uptake. Required for normal vision.
    分子量
    95468 Da
    基因ID
    2916
    UniProt
    O15303
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