GABBR1 抗体 (Extracellular)
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- 抗原 See all GABBR1 抗体
- GABBR1 (gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1))
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抗原表位
- AA 66-79, Extracellular
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GABBR1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Live Cell Imaging (LCI)
- 原理
- A Rabbit Polyclonal Antibody to GABA(B) Receptor 1
- 特异性
- Extracellular, N-terminus
- 交叉反应
- 人, 小鼠, 大鼠
- 交叉反应 （详细）
- Does not recognize alternative splice 1b.
- 预测反应
- Mouse,human,canine,bovine - identical
- 产品特性
- Anti-GABA(B) R1 (extracellular) Antibody is directed against an epitope of rat GABA(B) receptor 1. Anti-GABA(B) R1 (extracellular) Antibody (ABIN7043195, ABIN7044319 and ABIN7044320) can be used in western blot and immunohistochemistry applications. It has been designed to recognize GABBR1 from human, rat, and mouse samples.
- 纯化方法
- Affinity purified on immobilized antigen.
- 免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: CRGEREVVGPKVRK, corresponding to amino acid residues 66-79 of rat GABBR1
- 亚型
- IgG
- Top Product
- Discover our top product GABBR1 Primary Antibody
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anti-gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1) (AA 52-151) antibody
GABBR1 适用: 人 WB, ELISA, IF, RNAi 宿主: 小鼠 Monoclonal 2D7 unconjugated
anti-gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1) (C-Term) antibodyGABBR1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1) antibodyGABBR1 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1) (AA 873-977) antibodyGABBR1 适用: 大鼠 WB, IF, ICC 宿主: 小鼠 Monoclonal S93A-49 unconjugated
anti-gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1) (AA 873-977) antibody (HRP)GABBR1 适用: 大鼠 WB, IF, ICC 宿主: 小鼠 Monoclonal S93A-49 HRP
anti-gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1) (AA 873-977) antibody (FITC)GABBR1 适用: 大鼠 WB, IF, ICC 宿主: 小鼠 Monoclonal S93A-49 FITC
anti-gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1) (AA 873-977) antibody (Alkaline Phosphatase (AP))GABBR1 适用: 大鼠 WB, IF, ICC 宿主: 小鼠 Monoclonal S93A-49 Alkaline Phosphatase (AP)
anti-gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1) (AA 873-977) antibody (PerCP)GABBR1 适用: 大鼠 WB, IF, ICC 宿主: 小鼠 Monoclonal S93A-49 PerCP
anti-gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1) (AA 873-977) antibody (Atto 594)GABBR1 适用: 大鼠 WB, IF, ICC 宿主: 小鼠 Monoclonal S93A-49 Atto 594
anti-gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1) (AA 873-977) antibody (Atto 488)GABBR1 适用: 大鼠 WB, IF, ICC 宿主: 小鼠 Monoclonal S93A-49 Atto 488
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- 应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:100
Application Dilutions Western blot wb: 1:200
- 说明
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Negative Control: (ABIN7235523)
Blocking Peptide: (ABIN7235523)
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Recosntitute with double distilled water (DDW) to a concentration of 1.0 mg/mL.
- 浓度
- 1 mg/mL
- 缓冲液
- PBS pH 7.4
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- 抗原
- GABBR1 (gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1))
- 别名
- GABBR1 (GABBR1 产品)
- 背景
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γ-Aminobutyric acid type B receptor subunit 1, GABA B receptor 1, GABABR1, Gb1, GABBR1, GPRC3A,GABA (gamma-aminobutyric acid) is the major inhibitory neurotransmitter in the central nervous system and plays a crucial role in the modulation of neuronal activity.1,2The GABA transmitter interacts with three types of receptors: the ionotropic receptors, GABA(A) R and GABA(C) R, and the metabotropic GABA (B) receptor, [GABA(B) R].3 The latter belongs to the G-protein coupled receptor superfamily and mediates slow synaptic inhibition in the brain and spinal cord.1,4The functional GABA (B) receptor is a heterodimer consisting of two subunits, the GABA(B) R1 and the GABA(B) R2. These subunits were demonstrated to have complementary roles essential for the functional receptor.5,6 The GABA(B) R1 subunit was demonstrated to be important for agonist and antagonist binding, while GABA(B) R2 was shown to be essential for trafficking and for G-protein binding.To date, eight alternatively spliced isoforms of GABA (B) R1 have been proposed. These are named 1a-1h, of which 1a and 1b are the most prominent. Only 1a, 1b, and 1c appear to act as functional subunits.6,7 They are widespread, being expressed in the testis, stomach, spinal cord, and brain. Isoform 1b is also expressed in the kidney and liver.7
Alternative names: GABA(B) R1, gamma-Aminobutyric acid type B receptor subunit 1, GABA B receptor 1, GABABR1, Gb1, GABBR1, GPRC3A - 基因ID
- 81657
- NCBI登录号
- NM_001319053
- UniProt
- Q9Z0U4
- 途径
- Positive Regulation of Peptide Hormone Secretion, cAMP Metabolic Process
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