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Ephrin A5 抗体 (Extracellular)

EFNA5 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7043130
发货至: 中国
  • 抗原 See all Ephrin A5 (EFNA5) 抗体
    Ephrin A5 (EFNA5)
    抗原表位
    • 15
    • 7
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 172-186, Extracellular
    适用
    • 41
    • 34
    • 25
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 43
    • 5
    克隆类型
    • 44
    • 4
    多克隆
    标记
    • 22
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Ephrin A5 antibody is un-conjugated
    应用范围
    • 37
    • 21
    • 13
    • 13
    • 10
    • 7
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    原理
    A Rabbit Polyclonal Antibody to Ephrin A5
    特异性
    Extracellular
    交叉反应
    人, 小鼠, 大鼠
    预测反应
    Mouse,rat - identical
    产品特性
    Anti-Ephrin-A5 (extracellular) Antibody (ABIN7043130, ABIN7044259 and ABIN7044260) is a highly specific antibody directed against an epitope of human EFNA5. The antibody can be used in western blot and immunohistochemistry applications. It has been designed to recognize EFNA5 from rat, mouse, and human samples.
    纯化方法
    Affinity purified on immobilized antigen.
    免疫原

    Immunogen: Synthetic peptide

    Immunogen Sequence: (C)DRVFDVNDKVENSLE, corresponding to amino acid residues 172-186 of human Ephrin-A5

    亚型
    IgG
    Top Product
    Discover our top product EFNA5 Primary Antibody
  • 应用备注

    Antigen preadsorption control: 1 μg peptide per 1 μg antibody

    Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:200

    Application Dilutions Western blot wb: 1:200

    说明

    Negative Control: (ABIN7235310)

    Blocking Peptide: (ABIN7235310)

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Recosntitute with double distilled water (DDW) to a concentration of 1.0 mg/mL.
    浓度
    1 mg/mL
    缓冲液
    PBS pH 7.4
    储存条件
    4 °C,-20 °C
    储存方法

    Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.

    Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

  • 抗原
    Ephrin A5 (EFNA5)
    别名
    EFNA5 (EFNA5 产品)
    背景
    EPH-related receptor tyrosine kinase ligand 7, LERK7, AL-1, EFNA5,The Eph family of tyrosine kinase receptor signaling pathway is important for a variety of physiological processes during development including cell morphology, proliferation, migration and axonal guidance, dendritic spine formation and neural plasticity. Eph receptors mediate forward signaling in one cell while ephrin ligands transmit reverse signaling in an adjacent cell1-3.Eph receptors consist of two large subfamilies: EphA and EphB that bind to either glycophosphatidylinositol (GPI)-anchored ephrin-A ligands or transmembrane ephrin-B ligands respectively. Ephrin ligands are divided into ephrin-A (1 to 5) and ephrin-B (1 to 3)1,2.Ephrin-A5 is predominantly expressed in the quiescent anterior lens epithelial cells and is highly expressed in different layers of the cortex2,3.Studies show that mutations in ephrin-A5 are linked to congenital and age-related cataracts in humans and mice. Loss of ephrin-A5 causes abnormal localization of E-cadherin and β-catenin in anterior epithelial cells and epithelial-mesenchymal-transition2.

    Alternative names: Ephrin A5, EPH-related receptor tyrosine kinase ligand 7, LERK7, AL-1, EFNA5
    基因ID
    1946
    NCBI登录号
    NM_001962
    UniProt
    P52803
    途径
    RTK signaling
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