Ephrin A5 抗体 (Extracellular)
Quick Overview for Ephrin A5 抗体 (Extracellular) (ABIN7043130)
抗原
See all Ephrin A5 (EFNA5) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 172-186, Extracellular
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原理
- A Rabbit Polyclonal Antibody to Ephrin A5
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特异性
- Extracellular
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Mouse,rat - identical
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产品特性
- Anti-Ephrin-A5 (extracellular) Antibody (ABIN7043130, ABIN7044259 and ABIN7044260) is a highly specific antibody directed against an epitope of human EFNA5. The antibody can be used in western blot and immunohistochemistry applications. It has been designed to recognize EFNA5 from rat, mouse, and human samples.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: (C)DRVFDVNDKVENSLE, corresponding to amino acid residues 172-186 of human Ephrin-A5
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亚型
- IgG
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anti-Ephrin A5 (EFNA5) (AA 114-203) antibody
EFNA5 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 1F12 unconjugated
anti-Ephrin A5 (EFNA5) (AA 114-203) antibodyEFNA5 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Ephrin A5 (EFNA5) (Internal Region) antibodyEFNA5 适用: 人, 大鼠, 小鼠 ELISA, WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ephrin A5 (EFNA5) antibodyEFNA5 适用: 人, 大鼠, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ephrin A5 (EFNA5) (AA 21-203) antibodyEFNA5 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ephrin A5 (EFNA5) (Center) antibodyEFNA5 适用: 人, 大鼠, 小鼠, Cow, 兔, 小鸡 WB, IHC, IF, FACS, IC 宿主: 兔 Polyclonal unconjugated
anti-Ephrin A5 (EFNA5) (AA 31-80) antibodyEFNA5 适用: 人, 大鼠, 小鼠 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ephrin A5 (EFNA5) (C-Term) antibodyEFNA5 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Ephrin A5 (EFNA5) (C-Term) antibodyEFNA5 适用: 人, 大鼠, 小鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Ephrin A5 (EFNA5) (Internal Region) antibodyEFNA5 适用: 人, 大鼠, 小鼠 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:200
Application Dilutions Western blot wb: 1:200
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说明
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Negative Control: (ABIN7235310)
Blocking Peptide: (ABIN7235310)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Recosntitute with double distilled water (DDW) to a concentration of 1.0 mg/mL.
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4
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储存条件
- 4 °C,-20 °C
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储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- Ephrin A5 (EFNA5)
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别名
- EFNA5
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背景
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EPH-related receptor tyrosine kinase ligand 7, LERK7, AL-1, EFNA5,The Eph family of tyrosine kinase receptor signaling pathway is important for a variety of physiological processes during development including cell morphology, proliferation, migration and axonal guidance, dendritic spine formation and neural plasticity. Eph receptors mediate forward signaling in one cell while ephrin ligands transmit reverse signaling in an adjacent cell1-3.Eph receptors consist of two large subfamilies: EphA and EphB that bind to either glycophosphatidylinositol (GPI)-anchored ephrin-A ligands or transmembrane ephrin-B ligands respectively. Ephrin ligands are divided into ephrin-A (1 to 5) and ephrin-B (1 to 3)1,2.Ephrin-A5 is predominantly expressed in the quiescent anterior lens epithelial cells and is highly expressed in different layers of the cortex2,3.Studies show that mutations in ephrin-A5 are linked to congenital and age-related cataracts in humans and mice. Loss of ephrin-A5 causes abnormal localization of E-cadherin and β-catenin in anterior epithelial cells and epithelial-mesenchymal-transition2.
Alternative names: Ephrin A5, EPH-related receptor tyrosine kinase ligand 7, LERK7, AL-1, EFNA5 -
基因ID
- 1946
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NCBI登录号
- NM_001962
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UniProt
- P52803
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途径
- RTK signaling
抗原
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