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- 抗原 See all DPP10 抗体
- DPP10 (Dipeptidylpeptidase 10 (DPP10))
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抗原表位
- AA 356-370, Extracellular
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DPP10 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- 原理
- A Rabbit Polyclonal Antibody to Dipeptidyl Peptidase 10
- 特异性
- Extracellular, C-terminus
- 交叉反应
- 人, 小鼠, 大鼠
- 预测反应
- 15 amino acid residues identical,Mouse - 14, human - 12
- 产品特性
- Anti-DPP10 (extracellular) Antibody (ABIN7043099, ABIN7045044 and ABIN7045045)) is a highly specific antibody directed against an epitope of the rat protein. The antibody can be used in western blot and immunohistochemistry applications. The antibody recognizes an extracellular epitope and is thus ideal for detecting the protein in living cells. It has been designed to recognize DPP10 from rat, mouse, and human samples.
- 纯化方法
- Affinity purified on immobilized antigen.
- 免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: CSRKYEMTSDTWISK, corresponding to amino acid residues 356-370 of rat DPP10
- 亚型
- IgG
- Top Product
- Discover our top product DPP10 Primary Antibody
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anti-Dipeptidylpeptidase 10 (DPP10) (Internal Region) antibody
DPP10 适用: 人, 马, Cow, 犬, 猴, 豚鼠 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Dipeptidylpeptidase 10 (DPP10) (Internal Region) antibodyVerified DPP10 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Dipeptidylpeptidase 10 (DPP10) (Extracellular Domain) antibodyDPP10 适用: 人, 马, Cow, 犬, 猴, Pig, 兔, Bat IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Dipeptidylpeptidase 10 (DPP10) (C-Term) antibodyDPP10 适用: 人, 马, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Dipeptidylpeptidase 10 (DPP10) (AA 400-500) antibodyDPP10 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Dipeptidylpeptidase 10 (DPP10) (AA 150-177) antibodyDPP10 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB23704 unconjugated
anti-Dipeptidylpeptidase 10 (DPP10) (AA 150-177) antibodyDPP10 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:1000
Application Dilutions Western blot wb: 1:200-1:400
- 说明
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Cited Application: IP
Negative Control: BLP-PC147
Blocking Peptide: BLP-PC147
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- 0.2 mL double distilled water (DDW).
- 浓度
- 1 mg/mL
- 缓冲液
- PBS pH 7.4
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- 抗原
- DPP10 (Dipeptidylpeptidase 10 (DPP10))
- 别名
- DPP10 (DPP10 产品)
- 背景
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Inactive dipeptidyl peptidase 10, Dipeptidyl peptidase X, DPP X, DPPY, DPL2, DPRP3,Dipeptidyl peptidase 10 (DPP10, DPPY) is a member of the prolyl oligopeptidase family (shares a 30 % sequence identity with DPP4) and belongs to the S9B serine protease subfamily. DPP10 is a homologous glycosylated, single-pass type II transmembrane protein that lacks the crucial serine residue of the catalytic triad. Unlike other KV4 subunits such as DPP6, DPP10 has a restricted expression pattern including the brain, adrenal gland and pancreas. The presence of DPP10 in endocrine cells suggests that the protein may also have an additional function related to the regulation of hormone secretion. DPP10 accelerates the activation and inactivation of KV4.3 channel gating with distinct biophysical properties.DPP10 associates with the α-subunits of the KV4 subfamily to form a ternary complex of approximately 750 kDa1. In addition, DPP10 forms complexes with other auxiliary subunits of the KV4 channels. In dorsal root ganglion DPP10 is co-localized with K+ channel-interacting proteins 1 and 2 (KChIPs) in the somatic surface and cytoplasm of KV4.3 nociceptors. Recently it has been hypothesized that KV4/KChIP/DPPL ternary complexes exist in subthreshold A-type K+ currents (Isas) expressing nociceptors and pain-modulating spinal interneurons2.DPP10 has been implicated in various pathologies. Aggregation of the protein is associated with neurodegenerative conditions such as Alzheimer's, diffuse Lewy body disease and fronto-temporal dementia3.
Alternative names: DPP10, Inactive dipeptidyl peptidase 10, Dipeptidyl peptidase X, DPP X, DPPY, DPL2, DPRP3 - 基因ID
- 363972
- NCBI登录号
- NM_020868
- UniProt
- Q6Q629
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