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- 抗原 See all CLIC4 抗体
- CLIC4 (Chloride Intracellular Channel 4 (CLIC4))
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抗原表位
- AA 8-20, Intracellular
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CLIC4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunochromatography (IC)
- 原理
- A Rabbit Polyclonal Antibody to CLIC4 Channel
- 特异性
- Intracellular, N-terminus
- 交叉反应
- 人, 小鼠, 大鼠
- 预测反应
- Rat,mouse - identical
- 产品特性
- Anti-CLIC4 Antibody (ABIN7043057 and ABIN7044140) is a highly specific antibody directed against an epitope of the human protein. The antibody can be used in western blot and immunocytochemistry applications. It has been designed to recognize CLIC4 from mouse, rat, and human samples.
- 纯化方法
- Affinity purified on immobilized antigen.
- 免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: (C)NGLKEEDKEPLIE, corresponding to amino acid residues 8-20 of human CLIC4
- 亚型
- IgG
- Top Product
- Discover our top product CLIC4 Primary Antibody
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anti-Chloride Intracellular Channel 4 (CLIC4) (AA 1-253) antibody
CLIC4 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Chloride Intracellular Channel 4 (CLIC4) (AA 1-253) antibodyCLIC4 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Chloride Intracellular Channel 4 (CLIC4) (N-Term) antibodyVerified CLIC4 适用: 人, 小鼠 WB, IHC, ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-Chloride Intracellular Channel 4 (CLIC4) (AA 104-253) antibodyCLIC4 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chloride Intracellular Channel 4 (CLIC4) (N-Term) antibodyCLIC4 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Chloride Intracellular Channel 4 (CLIC4) (N-Term) antibodyCLIC4 适用: 人, 小鼠, 大鼠, 豚鼠, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chloride Intracellular Channel 4 (CLIC4) antibodyCLIC4 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Chloride Intracellular Channel 4 (CLIC4) (N-Term) antibodyCLIC4 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Chloride Intracellular Channel 4 (CLIC4) (N-Term) antibodyCLIC4 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Chloride Intracellular Channel 4 (CLIC4) antibodyCLIC4 适用: 人 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: N/A
Application Dilutions Western blot wb: 1:200
- 说明
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Negative Control: (ABIN7235106)
Blocking Peptide: (ABIN7235106)
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Recosntitute with double distilled water (DDW) to a concentration of 1.0 mg/mL.
- 浓度
- 1 mg/mL
- 缓冲液
- PBS pH 7.4
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- 抗原
- CLIC4 (Chloride Intracellular Channel 4 (CLIC4))
- 别名
- CLIC4 (CLIC4 产品)
- 背景
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Cl- intracellular channel 4, Intracellular chloride ion channel p64H1,Chloride intracellular channel (CLIC) is a family of proteins encoded by six different genes (CLIC1-6)1-3.The localization of the various CLIC channels remains elusive and controversial since they can be either found in a soluble form in the cytoplasm or as integral membrane proteins (in intracellular compartments such as the nuclear membrane or the endoplasmic reticulum for example, or associated with the plasma membrane) via their single transmembrane domain1.When membrane associated, CLIC channels indeed function as ion channels (enabling the passage of Cl- ions). Non-channel functions are also attributed to CLICs and include cell cycle regulation, cell differentiation, and apoptosis. These different roles depend on whether CLICs are membrane bound or cytosolic1. For instance, CLIC4 is involved in keratinocyte differentiation in a TGFb-dependent manner4,5, in such a way that TGFb stimulation induces the expression and nuclear localization of CLIC4 and its subsequent interaction with transcription factors4. CLIC4 is also required for growth arrest and apoptosis under stress6.CLIC4 distribution is rather ubiquitous but shows higher expression level in the skin, kidney, brain and testes7.
Alternative names: CLIC4, Cl- intracellular channel 4, Intracellular chloride ion channel p64H1 - 基因ID
- 25932
- NCBI登录号
- NM_013943
- UniProt
- Q9Y696
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