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Chloride Channel 5 抗体 (Extracellular)

CLCN5 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7043053
发货至: 中国
  • 抗原 See all Chloride Channel 5 (CLCN5) 抗体
    Chloride Channel 5 (CLCN5)
    抗原表位
    • 15
    • 9
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 401-415, Extracellular
    适用
    • 44
    • 13
    • 12
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    大鼠
    宿主
    • 43
    • 4
    克隆类型
    • 44
    • 3
    多克隆
    标记
    • 18
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Chloride Channel 5 antibody is un-conjugated
    应用范围
    • 20
    • 17
    • 13
    • 13
    • 6
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    原理
    A Rabbit Polyclonal Antibody to CLC-5 (CLCN5) Channel
    特异性
    Extracellular
    交叉反应
    小鼠, 大鼠
    预测反应
    Mouse - identical, human - 14,15 amino acid residues identical
    产品特性
    Anti- Antibody (ABIN7043053 and ABIN7044124) is a highly specific antibody directed against an epitope of the rat protein. The antibody can be used in western blot and immunohistochemistry applications. It has been designed to recognize from human, mouse, and rat samples.
    纯化方法
    Affinity purified on immobilized antigen.
    免疫原

    Immunogen: Synthetic peptide

    Immunogen Sequence: CDYENHFNTSKGGEL, corresponding to amino acid residues 401-415 of rat CLCN5 

    亚型
    IgG
    Top Product
    Discover our top product CLCN5 Primary Antibody
  • 应用备注

    Antigen preadsorption control: 1 μg peptide per 1 μg antibody

    Application Dilutions Immunohistochemistry paraffin embedded sections ihc: N/A

    Application Dilutions Western blot wb: 1:200

    说明

    Negative Control: (ABIN7235090)

    Blocking Peptide: (ABIN7235090)

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Recosntitute with double distilled water (DDW) to a concentration of 1.0 mg/mL.
    浓度
    1 mg/mL
    缓冲液
    PBS pH 7.4
    储存条件
    4 °C,-20 °C
    储存方法

    Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.

    Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

  • 抗原
    Chloride Channel 5 (CLCN5)
    别名
    CLCN5 (CLCN5 产品)
    背景
    CLCN5, Chloride channel 5, Chloride transporter ClC-5, H+/Cl- exchange transporter 5, DENTS,CLC5 is a member of the voltage-dependent Cl- channel family that includes nine known members. Based on sequence similarity, CLC5 is closely linked to the CLC3 and CLC4 subunits. CLC-5 is mainly found in intracellular vesicles, particularly in early endosomes, where it is believed to contribute to their acidification.The channel is mainly expressed in the kidney, although it has also been found in the small intestine, brain and liver.Mutations in the CLC5 gene cause Dent's disease, an X-linked renal disorder.

    Alternative names: CLC-5, CLCN5, Chloride channel 5, Chloride transporter ClC-5, H+/Cl- exchange transporter 5, DENTS
    基因ID
    25749
    NCBI登录号
    NM_000084
    UniProt
    P51796
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