Chloride Channel 5 抗体 (Extracellular)
Quick Overview for Chloride Channel 5 抗体 (Extracellular) (ABIN7043053)
抗原
See all Chloride Channel 5 (CLCN5) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 401-415, Extracellular
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原理
- A Rabbit Polyclonal Antibody to CLC-5 (CLCN5) Channel
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特异性
- Extracellular
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交叉反应
- 小鼠, 大鼠
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预测反应
- Mouse - identical, human - 14,15 amino acid residues identical
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产品特性
- Anti- Antibody (ABIN7043053 and ABIN7044124) is a highly specific antibody directed against an epitope of the rat protein. The antibody can be used in western blot and immunohistochemistry applications. It has been designed to recognize from human, mouse, and rat samples.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: CDYENHFNTSKGGEL, corresponding to amino acid residues 401-415 of rat CLCN5
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亚型
- IgG
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anti-Chloride Channel 5 (CLCN5) (Middle Region) antibody
CLCN5 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 绵羊, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Chloride Channel 5 (CLCN5) antibodyCLCN5 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Chloride Channel 5 (CLCN5) (AA 15-41), (N-Term) antibodyCLCN5 适用: 人 WB 宿主: 兔 Polyclonal RB42009 unconjugated
anti-Chloride Channel 5 (CLCN5) (Internal Region) antibodyCLCN5 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chloride Channel 5 (CLCN5) (AA 553-746) antibodyCLCN5 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chloride Channel 5 (CLCN5) (AA 566-665) antibodyCLCN5 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Chloride Channel 5 (CLCN5) (AA 521-570) antibodyCLCN5 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 绵羊 WB 宿主: 兔 Polyclonal unconjugated
anti-Chloride Channel 5 (CLCN5) (AA 637-816) antibodyCLCN5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: N/A
Application Dilutions Western blot wb: 1:200
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说明
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Negative Control: (ABIN7235090)
Blocking Peptide: (ABIN7235090)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Recosntitute with double distilled water (DDW) to a concentration of 1.0 mg/mL.
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4
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储存条件
- 4 °C,-20 °C
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储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- Chloride Channel 5 (CLCN5)
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别名
- CLCN5
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背景
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CLCN5, Chloride channel 5, Chloride transporter ClC-5, H+/Cl- exchange transporter 5, DENTS,CLC5 is a member of the voltage-dependent Cl- channel family that includes nine known members. Based on sequence similarity, CLC5 is closely linked to the CLC3 and CLC4 subunits. CLC-5 is mainly found in intracellular vesicles, particularly in early endosomes, where it is believed to contribute to their acidification.The channel is mainly expressed in the kidney, although it has also been found in the small intestine, brain and liver.Mutations in the CLC5 gene cause Dent's disease, an X-linked renal disorder.
Alternative names: CLC-5, CLCN5, Chloride channel 5, Chloride transporter ClC-5, H+/Cl- exchange transporter 5, DENTS -
基因ID
- 25749
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NCBI登录号
- NM_000084
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UniProt
- P51796
抗原
-
