AQP3 抗体 (Intracellular)
Quick Overview for AQP3 抗体 (Intracellular) (ABIN7042937)
抗原
See all AQP3 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 275-292, Intracellular
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原理
- A Rabbit Polyclonal Antibody to Aquaporin 3 Channel
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特异性
- Intracellular, C-terminus
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- 18 amino acid residues identical, sheep,human - 15,Mouse - 17
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产品特性
- Anti-Aquaporin 3 Antibody (ABIN7042937, ABIN7045198 and ABIN7045199) is a highly specific antibody directed against an epitope of the rat protein. The antibody can be used in western blot, immunoprecipitation, indirect flow cytometry, and immunohistochemistry applications. It has been designed to recognize the AQP3 channel from rat, human, and mouse samples.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: (C)STEAENVKLAHMKHKEQI, corresponding to amino acid residues 275-292 of rat AQP3
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亚型
- IgG
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anti-Aquaporin 3 (Gill Blood Group) (AQP3) (AA 178-292) antibody
AQP3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Aquaporin 3 (Gill Blood Group) (AQP3) (C-Term) antibodyAQP3 适用: 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Aquaporin 3 (Gill Blood Group) (AQP3) (AA 278-292), (C-Term) antibodyAQP3 适用: 人, 大鼠, 小鼠 WB, IHC, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Aquaporin 3 (Gill Blood Group) (AQP3) (AA 201-292) antibodyAQP3 适用: 人, 大鼠, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Aquaporin 3 (Gill Blood Group) (AQP3) (AA 210-244) antibodyAQP3 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Aquaporin 3 (Gill Blood Group) (AQP3) (AA 268-292) antibodyAQP3 适用: 人, 大鼠, 小鼠 WB, IHC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Aquaporin 3 (Gill Blood Group) (AQP3) (AA 163-191) antibodyAQP3 适用: 人, 小鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Aquaporin 3 (Gill Blood Group) (AQP3) (C-Term) antibody (HRP)AQP3 适用: 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal HRP
anti-Aquaporin 3 (Gill Blood Group) (AQP3) (C-Term) antibody (FITC)AQP3 适用: 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal FITC
anti-Aquaporin 3 (Gill Blood Group) (AQP3) (C-Term) antibody (Biotin)AQP3 适用: 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal Biotin
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应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: N/A
Application Dilutions Western blot wb: 1:200
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说明
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Cited Application: IHC|IFC
Negative Control: (ABIN7234763)
Blocking Peptide: (ABIN7234763)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 0.2 mL double distilled water (DDW).
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4
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储存条件
- 4 °C,-20 °C
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储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- AQP3 (Aquaporin 3 (Gill Blood Group) (AQP3))
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别名
- AQP3
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背景
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AQP3, Aquaglyceroporin-3, GIL, GLIP,Aquaporin 3 (AQP-3) belongs to a family of membrane proteins that allow the passage of water and certain other solutes through biological membranes. The family is composed of 13 members (AQP-0 to AQP-12).The aquaporins can be divided into two functional groups based on their permability characteristics: the aquaporins that are only permeated by water and the aquaglyceroporins that are permeated by water and other small solutes such as glycerol. This last group includes AQP-3 as well as AQP-7, AQP-9 and AQP-10.1 Little is known about the function of the two newest members, AQP-11 and AQP-12. The proteins present a conserved structure of six transmembrane domains with intracellular N- and C-termini. The functional channel is a tetramer but each subunit has a separate pore and therefore the functional channel unit, contains four pores.1AQP-3 is widely expressed in several organs with prominent expression found in the skin, colon, lung and kidney. Consistent with a central function of AQP-3 in skin, mice deficient in AQP-3 have reduced skin water content and elasticity compared with wild-type mice, as well as impaired wound healing and epidermal biosynthesis.2 Furthermore, AQP-3 deficient mice were found to be resistant to skin tumor development suggesting a role for this aquaporin in tumorigenesis.3
Alternative names: Aquaporin 3, AQP3, Aquaglyceroporin-3, GIL, GLIP -
基因ID
- 65133
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NCBI登录号
- NM_004925
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UniProt
- P47862
抗原
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