ADRA1B 抗体 (Extracellular)
Quick Overview for ADRA1B 抗体 (Extracellular) (ABIN7042897)
抗原
See all ADRA1B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 21-35, Extracellular
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原理
- A Rabbit Polyclonal Antibody to α1B-Adrenergic Receptor
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特异性
- Extracellular, N-terminus
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- 15 amino acid residues identical, rat - 13,Mouse - 14
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产品特性
- Anti-α1B-Adrenergic Receptor (extracellular) Antibody (ABIN7042897, ABIN7043914 and ABIN7043915) is a highly specific antibody directed against an extracellular epitope of the human α1B-adrenoceptor. The antibody can be used in western blot, immunohistochemistry, live cell imaging and indirect flow cytometry applications. It has been designed to recognize α1B-adrenoceptor from human, rat and mouse samples.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: (C)KNANFTGPNQTSSNS, corresponding to amino acid residues 21-35 of human alpha1B-adrenoceptor
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亚型
- IgG
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anti-Adrenergic, alpha-1B-, Receptor (ADRA1B) antibody
ADRA1B 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, alpha-1B-, Receptor (ADRA1B) antibodyADRA1B 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, alpha-1B-, Receptor (ADRA1B) (Cytoplasmic Domain) antibodyADRA1B 适用: 人, 小鼠, 大鼠, 犬, Cow, Pig, 猴, Hamster, 马 ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, alpha-1B-, Receptor (ADRA1B) (AA 169-218) antibodyADRA1B 适用: 人, 小鼠, 大鼠, 犬, Pig, 猴, 豚鼠, 兔, Hamster, 马, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, alpha-1B-, Receptor (ADRA1B) (AA 388-437) antibodyADRA1B 适用: 人, 小鼠, 大鼠, 犬, Cow, Pig, 猴, 豚鼠, 兔, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, alpha-1B-, Receptor (ADRA1B) (AA 1-100) antibodyADRA1B 适用: 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, alpha-1B-, Receptor (ADRA1B) (C-Term) antibodyADRA1B 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, alpha-1B-, Receptor (ADRA1B) antibodyADRA1B 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, alpha-1B-, Receptor (ADRA1B) (Cytoplasmic Domain) antibodyADRA1B 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Adrenergic, alpha-1B-, Receptor (ADRA1B) (C-Term) antibodyADRA1B 适用: 人, 小鼠, 大鼠, 犬, Cow, 猴, Hamster IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:100
Application Dilutions Western blot wb: 1:200
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说明
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Cited Application: IHC
Negative Control: (ABIN7234661)
Blocking Peptide: (ABIN7234661)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Recosntitute with double distilled water (DDW) to a concentration of 1.0 mg/mL.
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4
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储存条件
- 4 °C,-20 °C
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储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- ADRA1B (Adrenergic, alpha-1B-, Receptor (ADRA1B))
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别名
- ADRA1B
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背景
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Alpha-1B adrenoceptor, ADA1B, ADRA1B,Adrenergic receptors (also called adrenoceptors) are the receptors for the catecholamines adrenaline and noradrenaline (called epinephrine and norepinephrine in the United States). Adrenaline and noradrenaline play important roles in the control of blood pressure, myocardial contractile rate and force, airway reactivity, and a variety of metabolic and central nervous system functions. Adrenergic receptors are members of the G-protein coupled receptor (GPCR) superfamily of membrane proteins. They share a common structure of seven putative transmembrane domains, an extracellular amino terminus, and a cytoplasmic carboxyl terminus.Adrenoceptors are divided into three types: α1, α2 and β adrenoceptors. Each type is further divided into at least three subtypes: α1A, α1B, α1D, α2A, α2B, α2C, β1, β2, β3.1,2 They are expressed in nearly all peripheral tissues and in the central nervous system.1,2 All α1-adrenoceptors (α1-ARs) activate phospholipases C and A2.3 In addition to mobilizing intracellular calcium, the α1-ARs have also been shown to activate calcium influx via voltage-dependent and -independent calcium channels.4 α1B-Adrenergic receptor populations are greatest in the spleen, kidney, cerebellum, and fetal brain.5α1B-Adrenoceptor causes contraction of smooth muscle cells and thereby controls vascular tone, blood pressure, and accelerates the development of atherosclerosis.5
Alternative names: alpha1B-Adrenergic Receptor, Alpha-1B adrenoceptor, ADA1B, ADRA1B -
基因ID
- 147
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NCBI登录号
- NM_000679
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UniProt
- P35368
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途径
- AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
抗原
-
