Adenosine A3 Receptor 抗体 (AA 216-230)
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- 抗原 See all Adenosine A3 Receptor (ADORA3) 抗体
- Adenosine A3 Receptor (ADORA3)
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抗原表位
- AA 216-230
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Adenosine A3 Receptor antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunochromatography (IC)
- 原理
- A Rabbit Polyclonal Antibody to Adenosine A3 Receptor
- 特异性
- 3rd intracellular loop
- 交叉反应
- 人, 大鼠
- 预测反应
- Rat,mouse - 14,16 amino acid residues identical
- 产品特性
- Anti-Adenosine A3 Receptor Antibody is directed against an intracellular epitope of the human adenosine A3 receptor (A3AR). Anti-Adenosine A3 Receptor Antibody (ABIN7042891, ABIN7043892 and ABIN7043893)) can be used in western blot analysis, as well as immunocytochemical and immunohistocemical applications, and has been designed to recognize A3AR from human, rat, and mouse samples.
- 纯化方法
- Affinity purified on immobilized antigen.
- 免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: (C)KETGAFYGREFKTAK, corresponding to amino acid residues 216-230 of human A3AR
- 亚型
- IgG
- Top Product
- Discover our top product ADORA3 Primary Antibody
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anti-Adenosine A3 Receptor (ADORA3) (AA 85-180) antibody
ADORA3 适用: 人, 大鼠 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Adenosine A3 Receptor (ADORA3) (C-Term) antibodyADORA3 适用: 人 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Adenosine A3 Receptor (ADORA3) antibodyADORA3 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Adenosine A3 Receptor (ADORA3) (AA 121-225) antibodyADORA3 适用: 人 ELISA 宿主: 小鼠 Monoclonal 1A3 unconjugated
anti-Adenosine A3 Receptor (ADORA3) (C-Term) antibodyADORA3 适用: 人, Pig, Cow, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Adenosine A3 Receptor (ADORA3) (AA 202-232) antibodyADORA3 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB53326 unconjugated
anti-Adenosine A3 Receptor (ADORA3) (Cytoplasmic Domain) antibodyADORA3 适用: 人, Pig, 犬, 马, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Adenosine A3 Receptor (ADORA3) (C-Term) antibodyADORA3 适用: 人, 小鼠 WB, ELISA, IF, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Adenosine A3 Receptor (ADORA3) (AA 247-296) antibodyADORA3 适用: 人, Pig, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-Adenosine A3 Receptor (ADORA3) (AA 195-244) antibodyADORA3 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:50
Application Dilutions Western blot wb: 1:200
- 说明
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Negative Control: BLP-AR004
Blocking Peptide: BLP-AR004
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- 0.2 mL double distilled water (DDW).
- 浓度
- 1 mg/mL
- 缓冲液
- PBS pH 7.4
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- 抗原
- Adenosine A3 Receptor (ADORA3)
- 别名
- ADORA3 (ADORA3 产品)
- 背景
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ADORA3, A3AR, Adenosine A3R,Adenosine is an endogenous nucleoside generated locally in tissues under conditions of hypoxia, ischemia, or inflammation. It modulates a variety of physiological functions in many tissues including the brain and heart.1,2 Adenosine exerts its action via four specific adenosine receptors (also named P1 purinergic receptors): Adenosine A1 Receptor (A1AR), Adenosine A2A Receptor (A2AAR), Adenosine A2B Receptor (A2BAR), and Adenosine A3 Receptor (A3AR). The various adenosine receptors can be distinguished on the basis of their distinct molecular structures, distinct tissue distributions, and differential selectivity for adenosine analogs.1-4 All are integral membrane proteins and are members of the G protein-coupled receptor superfamily. They share a common structure of seven putative transmembrane domains, an extracellular amino terminus, a cytoplasmic carboxyl terminus, and a third intracellular loop important in binding G proteins.1-3Expression of A3AR has been reported in the brain, kidney, liver, and heart. It plays a role in modulation of cerebral ischemia, asthma, and cell growth. In addition, recent studies have established a cardioprotective role for A3AR.5 Expression of A3AR was reported to be elevated in cancerous tissues as well as in auto-immune inflammatory diseases.6,7 A patent has been filed for the use of A3AR and A3AR agonist as a diagnostic marker for therapeutic treatments of cancer and other diseases.
Alternative names: Adenosine A3 Receptor, ADORA3, A3AR, Adenosine A3R - 基因ID
- 140
- UniProt
- P0DMS8
- 途径
- Hormone Transport, cAMP Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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