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OGG1 抗体 (AA 151-250)

Cited in 1 publication. This 兔 多克隆 anti-OGG1 antibody specifically detects OGG1 in WB, ELISA, FACS, IHC (p) 和 IHC (fro). The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN702655
发货至: 中国
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Quick Overview for OGG1 抗体 (AA 151-250) (ABIN702655)

抗原

See all OGG1 抗体
OGG1 (8-Oxoguanine DNA Glycosylase (OGG1))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This OGG1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

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    AA 151-250

    交叉反应

    人, 小鼠, 大鼠

    预测反应

    Dog,Cow,Pig

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human OGG1/8 hydroxyguanine DNA glycosylase

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • Cogoi, Ferino, Miglietta, Pedersen, Xodo: "The regulatory G4 motif of the Kirsten ras (KRAS) gene is sensitive to guanine oxidation: implications on transcription." in: Nucleic acids research, Vol. 46, Issue 2, pp. 661-676, (2017) (PubMed).

  • 抗原

    OGG1 (8-Oxoguanine DNA Glycosylase (OGG1))

    别名

    OGG1

    背景

    Synonyms: 8 hydroxyguanine DNA glycosylase, 8 oxoguanine DNA glycosylase 1, 8-oxoguanine DNA glycosylase, AP lyase, DNA apurinic or apyrimidinic site lyase, DNA lyase, DNA-apurinic or apyrimidinic site lyase, HMMH, HOGG 1, HOGG1, MMH, MUTM, N-glycosylase, Ogg 1, OGH 1, OGH1, OGG1_HUMAN.

    Background: This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Many alternative splice variants for this gene have been described, but the full-length nature for every variant has not been determined. [provided by RefSeq, Aug 2008].

    基因ID

    4968

    途径

    DNA Damage Repair
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