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KEAP1 抗体 (AA 65-160)

Name: KEAP1 抗体 (AA 65-160)
SKU: ABIN702085
Availability: OutOfStock

Cited in 5+ publications. This anti-KEAP1 antibody is a 兔多克隆 antibody detecting KEAP1 in WB, ELISA, IHC (p), IF (cc), IF (p) 和 IHC (fro). Suitable for 人, 小鼠, 大鼠, Pig 和兔.

This image was generously provided by Yang Song, Ph. (KEAP1 抗体 (AA 65-160))

2 images

(5 references)

产品编号 ABIN702085

发货至: 中国

Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111

No. 88 KeChuang 6th Street

Beijing Economic Technological Development Area

Room 801-803

4A Biotech Co.,Ltd.

Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for KEAP1 抗体 (AA 65-160) (ABIN702085)

抗原

See all KEAP1 抗体

KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))

适用

人, 小鼠, 大鼠, Pig, 兔

宿主

兔

克隆类型

多克隆

标记

This KEAP1 antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Discover our top product KEAP1 Primary Antibody

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AA 65-160

交叉反应

人, 小鼠, Pig, 兔, 大鼠

预测反应

Dog,Cow

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human KEAP1

亚型

IgG
anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) antibody
KEAP1 适用: 人, 小鼠 WB, IHC, IHC (p), FACS 宿主: 小鼠 Monoclonal 1B4 unconjugated

anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) (AA 380-624) antibody
KEAP1 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 7G4B10 unconjugated

anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) (AA 380-624) antibody
KEAP1 适用: 人, 小鼠 ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 1F10B6 unconjugated

anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) (AA 380-624) antibody
KEAP1 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal unconjugated

anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) (C-Term) antibody
KEAP1 适用: 人, 小鼠, 大鼠, 兔, Cow, 犬, 马, 豚鼠, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) (AA 327-624) antibody
KEAP1 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) (AA 1-286) antibody
KEAP1 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated

anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) (AA 41-53) antibody
Verified KEAP1 适用: 人 ELISA, IHC, IF 宿主: 山羊 Polyclonal unconjugated

anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) antibody
KD Validated KEAP1 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 25GB495 unconjugated

anti-Kelch-Like ECH-Associated Protein 1 (KEAP1) (AA 1-624) antibody
KEAP1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Su, Liu, Wang, Wang, Song, Song: "The electrophilic character of quinones is essential for the suppression of Bach1." in: Toxicology, Vol. 387, pp. 17-26, (2017) (PubMed).

Kouam, Yuan, Njayou, He, Tsayem, Oladejo, Song, Moundipa, Gao: "Induction of Mkp-1 and Nuclear Translocation of Nrf2 by Limonoids from Khaya grandifoliola C.DC Protect L-02 Hepatocytes against Acetaminophen-Induced Hepatotoxicity." in: Frontiers in pharmacology, Vol. 8, pp. 653, (2017) (PubMed).

Chen, Lin, Liu, Hsu, Lin, Su: "Caveolin-1 Expression Ameliorates Nephrotic Damage in a Rabbit Model of Cholesterol-Induced Hypercholesterolemia." in: PLoS ONE, Vol. 11, Issue 4, pp. e0154210, (2016) (PubMed).

Su, Zhang, Song, Shi, Fu, Xia, Bai, Hu, Xu, Song, Song: "Tetrachlorobenzoquinone activates nrf2 signaling by keap1 cross-linking and ubiquitin translocation but not keap1-cullin3 complex dissociation." in: Chemical research in toxicology, Vol. 28, Issue 4, pp. 765-74, (2015) (PubMed).

Su, Xia, Shi, Song, Fu, Xiao, Chen, Lu, Sun, Wu, Yang, Li, Ye, Song, Song: "Neohesperidin Dihydrochalcone versus CCl?-Induced Hepatic Injury through Different Mechanisms: The Implication of Free Radical Scavenging and Nrf2 Activation." in: Journal of agricultural and food chemistry, Vol. 63, Issue 22, pp. 5468-75, (2015) (PubMed).
抗原

KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))

别名

KEAP1

背景

Synonyms: INrf2, KLHL19, Kelch-like ECH-associated protein 1, Cytosolic inhibitor of Nrf2, Kelch-like protein 19, KEAP1, KIAA0132
Background: Acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1 and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. Retains NFE2L2/NRF2 and may also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome.

基因ID

9817

UniProt

Q14145

途径

Maintenance of Protein Location