ULK1 抗体 (AA 951-1050) (Cy3)
Our Local Distributor
北京 101111
Quick Overview for ULK1 抗体 (AA 951-1050) (Cy3) (ABIN701443)
抗原
See all ULK1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 951-1050
-
交叉反应
- 人, 小鼠, 大鼠
-
预测反应
- Cow,Pig,Horse,Chicken,Rabbit
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic peptide derived from human ATG1/ULK1
-
亚型
- IgG
-
-
anti-Unc-51 Like Kinase 1 (ULK1) (AA 951-1050) antibody
ULK1 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Unc-51 Like Kinase 1 (ULK1) (AA 602-715) antibodyULK1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2H8 unconjugated
anti-Unc-51 Like Kinase 1 (ULK1) antibodyULK1 适用: 人, 小鼠 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Unc-51 Like Kinase 1 (ULK1) (pSer556) antibodyULK1 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Unc-51 Like Kinase 1 (ULK1) (AA 567-577) antibodyULK1 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Unc-51 Like Kinase 1 (ULK1) (AA 567-577) antibody (HRP)ULK1 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal HRP
anti-Unc-51 Like Kinase 1 (ULK1) (AA 567-577) antibody (FITC)ULK1 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal FITC
anti-Unc-51 Like Kinase 1 (ULK1) (AA 567-577) antibody (Biotin)ULK1 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal Biotin
anti-Unc-51 Like Kinase 1 (ULK1) (AA 567-577) antibody (PE)ULK1 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal PE
anti-Unc-51 Like Kinase 1 (ULK1) (AA 567-577) antibody (PerCP)ULK1 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal PerCP
-
-
应用备注
-
FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
-
有效期
- 12 months
-
-
- ULK1 (Unc-51 Like Kinase 1 (ULK1))
-
别名
- ATG1/ULK1
-
背景
-
Synonyms: ATG1, ATG1A, UNC51, hATG1, Unc51.1, Serine/threonine-protein kinase ULK1, Autophagy-related protein 1 homolog, Unc-51-like kinase 1, ULK1, KIAA722
Background: Serine/threonine-protein kinase involved in autophagy in response to starvation. Acts upstream of phosphatidylinositol 3-kinase PIK3C3 to regulate the formation of autophagophores, the precursors of autophagosomes. Part of regulatory feedback loops in autophagy: acts both as a downstream effector and negative regulator of mammalian target of rapamycin complex 1 (mTORC1) via interaction with RPTOR. Activated via phosphorylation by AMPK and also acts as a regulator of AMPK by mediating phosphorylation of AMPK subunits PRKAA1, PRKAB2 and PRKAG1, leading to negatively regulate AMPK activity. May phosphorylate ATG13/KIAA652 and RPTOR, however such data need additional evidences. Plays a role early in neuronal differentiation and is required for granule cell axon formation.
-
基因ID
- 8408
-
UniProt
- O75385
-
途径
- Regulation of Cell Size, Autophagy
抗原
-
