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CD21 抗体 (PerCP)

This anti-CD21 antibody is a 小鼠 单克隆 antibody detecting CD21 in FACS. Suitable for 人, Pig, Cow 和 犬.
产品编号 ABIN7013986
发货至: 中国

Quick Overview for CD21 抗体 (PerCP) (ABIN7013986)

抗原

See all CD21 (CR2) 抗体
CD21 (CR2) (Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2))

适用

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人, Pig, Cow, 犬

宿主

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小鼠

克隆类型

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单克隆

标记

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This CD21 antibody is conjugated to PerCP

应用范围

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Flow Cytometry (FACS)

克隆位点

LT21
  • 原理

    Anti-Hu CD21 PerCP

    特异性

    The antibody LT21 reacts with an extracellular epitope of CD21 (CR2), a 145 kDa transmembrane glycoprotein (complement C3d receptor - C3dR) expressed on B lymphocytes, follicular dendritic cells, some epithelial cells and a subsets of T lymphocytes. It is not expressed on immature B cells.

    纯化方法

    Purified antibody is conjugated with activated Peridinin-Chlorophyll Protein (PerCP) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

    免疫原

    IM9 human B-lymphoblastoid cell line

    亚型

    IgG1 kappa
  • 应用备注

    Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

    限制

    仅限研究用
  • 缓冲液

    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • 抗原

    CD21 (CR2) (Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2))

    别名

    CD21

    背景

    Complement C3d receptor 2,CD21 (complement receptor 2, CR2) binds C3 complement fragments, especially its breakdown fragments, which remain covalently attached to complement activating surfaces or antigen. CD21 has important roles in uptake and retention of immunocomplexes, survival of memory B cells and in development and maintenance of the humoral response to T-dependent antigens. CD21 also serves as a key receptor for Epstein-Barr virus binding and is involved in targeting prions to folicular dendritic cells and expediting neuroinvasion following peripheral exposure to prions. A soluble form of the CD21 (sCD21) is shed from the lymphocyte surface and retains its ability to bind respective ligands.,CR2, C3DR2, CVID7, SLEB9

    基因ID

    1380

    UniProt

    P20023

    途径

    Complement System
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