GZMB 抗体 (FITC)
Quick Overview for GZMB 抗体 (FITC) (ABIN7013929)
抗原
See all GZMB 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- Anti-Granzyme B FITC
-
特异性
- The mouse monoclonal antibody CLB-GB11 recognizes granzyme B, a 31 kDa serine protease expressed intracellularly in activated Tc cells and NK cells.
-
纯化方法
- Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
-
免疫原
- Human NK cell line YT-INDY-derived granzyme B
-
亚型
- IgG1
-
-
anti-Granzyme B (GZMB) (AA 21-247) antibody
GZMB 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Granzyme B (GZMB) (AA 73-187) antibodyGZMB 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal GZMB-3014 unconjugated
anti-Granzyme B (GZMB) (AA 21-130) antibodyGZMB 适用: 人, 小鼠 WB, ELISA, FACS, IHC (p), IF (p), IHC (fro), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Granzyme B (GZMB) (AA 1-247) antibodyGZMB 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Granzyme B (GZMB) (AA 73-187) antibodyGZMB 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal GZMB-3056 unconjugated
anti-Granzyme B (GZMB) antibodyGZMB 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Granzyme B (GZMB) antibodyGZMB 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal CLB-GB11 unconjugated
anti-Granzyme B (GZMB) (AA 21-247) antibodyGZMB 适用: 人 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 4E4 unconjugated
anti-Granzyme B (GZMB) (AA 21-247) antibodyGZMB 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal 2G12G7 unconjugated
anti-Granzyme B (GZMB) antibodyGZMB 适用: 人 ELISA, FACS, cELISA 宿主: 小鼠 Monoclonal GM-4C1 unconjugated
-
-
应用备注
- Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests. Intracellular staining.
-
限制
- 仅限研究用
-
-
-
缓冲液
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
储存方法
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
-
-
- GZMB (Granzyme B (GZMB))
-
别名
- Granzyme B
-
背景
- Granzyme B,Granzyme B is a serine protease that is expressed in cytoplasmic granules of cytotoxic T lymphocytes and NK cells. Vectorial secretion of perforin and granzymes is responsible for their granule-mediated cytotoxicity. Granzyme B plays a pivotal role in the induction of apoptosis in the target cells by activation of caspases. Moreover, granzyme B was reported to cleave directly alpha-tubulin, leading to perturbation of microtubule networks during the induced cell death.,GZMB, HLP, CTLA1, SECT
-
基因ID
- 3002
-
UniProt
- P10144
-
途径
- Apoptosis, Caspase Cascade in Apoptosis
抗原
-
