HDAC6 抗体
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北京 101111
Quick Overview for HDAC6 抗体 (ABIN7013923)
抗原
See all HDAC6 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-HDAC6 Purified
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特异性
- The mouse monoclonal antibody 3D2 recognizes D2 domain of human histone deacetylase 6 (HDAC6, intracellular antigen), amino acids 471-481.
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无交叉反应
- 小鼠, 斑马鱼
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纯化方法
- Purified by protein-A affinity chromatography.
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免疫原
- human HDAC6
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亚型
- IgG1 kappa
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应用备注
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Western blotting: Recommended dilution: 1-5 μg/mL.
Immunocytochemistry: Recommended dilution: 5-10 μg/mL. -
限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Do not freeze.
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- HDAC6 (Histone Deacetylase 6 (HDAC6))
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别名
- HDAC6
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背景
- Histone deacetylase 6,Histone deacetylase 6 (HDAC6), like other histone deacetylases, affects gene expression by regulation of chromatin remodeling. HDAC6 contains an internal duplication of two catalytic domains which appear to function independently of each other. Besides histones, HDAC6 deacetylates also other substrates including alpha tubulin and HSP90 alpha, and is involved in protein trafficking and degradation, as well as in affecting of cell shape and migration. Deregulation of HDAC6 expression and activity is associated with many diseases.,Histone deacetylase 6
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基因ID
- 10013
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UniProt
- Q9NSW6
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
抗原
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