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POLR2A/RPB1 抗体 (pSer5)

This anti-POLR2A/RPB1 antibody is a 兔 多克隆 antibody detecting POLR2A/RPB1 in WB, IHC 和 IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7265278
发货至: 中国

Quick Overview for POLR2A/RPB1 抗体 (pSer5) (ABIN7265278)

抗原

See all POLR2A/RPB1 (POLR2A) 抗体
POLR2A/RPB1 (POLR2A) (RNA Polymerase II Subunit RPB1 (POLR2A))

适用

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  • 41
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  • 6
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人, 小鼠, 大鼠

宿主

  • 76
  • 22
  • 1
  • 1
  • 1

克隆类型

  • 51
  • 50
多克隆

标记

  • 70
  • 5
  • 4
  • 4
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  • 4
  • 4
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  • 1
  • 1
This POLR2A/RPB1 antibody is un-conjugated

应用范围

  • 64
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  • 22
  • 10
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  • 6
  • 4
  • 3
  • 3
  • 2
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  • 1
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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

    • 20
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    • 11
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
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    • 1
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    • 1
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    pSer5

    产品特性

    Phosphorylated antibody

    纯化方法

    Affinity purification

    免疫原

    A phospho specific peptide corresponding to residues surrounding S5 of human POLR2A

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000 IHC 1:50-1:100 IF 1:50-1:100

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    POLR2A/RPB1 (POLR2A) (RNA Polymerase II Subunit RPB1 (POLR2A))

    别名

    POLR2A

    背景

    This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA.

    分子量

    Observed_MW: 260 kDa

    Calculated_MW: 63 kDa/217 kDa

    基因ID

    5430

    UniProt

    P24928

    途径

    Regulatory RNA Pathways
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