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FLT3 抗体 (pTyr589, pTyr591)

This anti-FLT3 antibody is a 兔 多克隆 antibody detecting FLT3 in WB. Suitable for 人.
产品编号 ABIN7265244
发货至: 中国

Quick Overview for FLT3 抗体 (pTyr589, pTyr591) (ABIN7265244)

抗原

See all FLT3 抗体
FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))

适用

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宿主

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克隆类型

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多克隆

标记

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This FLT3 antibody is un-conjugated

应用范围

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Western Blotting (WB)
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    pTyr589, pTyr591

    产品特性

    Phosphorylated antibody

    纯化方法

    Affinity purification

    免疫原

    A synthetic phosphorylated peptide around Y589 & Y591 of human FLT3 (NP_004110.2).

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))

    别名

    FLT3

    背景

    This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia.

    分子量

    Observed_MW: 113 kDa

    Calculated_MW: 108 kDa/112 kDa

    基因ID

    2322

    UniProt

    P36888

    途径

    RTK signaling
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