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Estrogen Receptor alpha 抗体 (pSer118)

This 兔 多克隆 antibody specifically detects Estrogen Receptor alpha in IHC 和 IF. It exhibits reactivity toward 人.
产品编号 ABIN7265108
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
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Quick Overview for Estrogen Receptor alpha 抗体 (pSer118) (ABIN7265108)

抗原

See all Estrogen Receptor alpha (ESR1) 抗体
Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

适用

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宿主

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克隆类型

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多克隆

标记

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This Estrogen Receptor alpha antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

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    pSer118

    产品特性

    Phosphorylated antibody

    纯化方法

    Affinity purification

    免疫原

    A phospho specific peptide corresponding to residues surrounding S118 of human Estrogen Receptor alpha

    亚型

    IgG
  • 应用备注

    IHC 1:50-1:100 IF 1:100-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

    别名

    Estrogen Receptor alpha

    背景

    This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined.

    基因ID

    2099

    UniProt

    P03372

    途径

    Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
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