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SAV1 抗体

The 兔 多克隆 anti-SAV1 antibody is suitable to detect SAV1 in samples from 人 和 小鼠. It has been validated for WB.
产品编号 ABIN7264996
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for SAV1 抗体 (ABIN7264996)

抗原

See all SAV1 抗体
SAV1 (Salvador Homolog 1 (SAV1))

适用

  • 26
  • 6
  • 5
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 20
  • 6
  • 1

克隆类型

  • 24
  • 3
多克隆

标记

  • 22
  • 1
  • 1
  • 1
  • 1
  • 1
This SAV1 antibody is un-conjugated

应用范围

  • 24
  • 15
  • 8
  • 5
  • 4
  • 2
  • 1
Western Blotting (WB)
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein of human SAV1 (NP_068590.1).

    亚型

    IgG
  • 应用备注

    WB 1:1000-1:4000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    SAV1 (Salvador Homolog 1 (SAV1))

    别名

    SAV1

    背景

    WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein with two WW domains, a SARAH domain, and a coiled-coil region and is ubiquitously expressed in adult tissues. This protein binds to MST1 (mammalian sterile 20-like kinase 1) and promotes MST1-induced apoptosis. It has also been shown to bind to HAX1 (hematopoietic cell-specific protein 1 (HS1)-associated protein X-1) and to attenuate the anti-apoptotic effects of HAX1. Studies in human and mouse suggest this gene acts as a tumor suppressor.

    分子量

    Observed_MW: 45 kDa

    Calculated_MW: 44 kDa

    基因ID

    60485

    UniProt

    Q9H4B6

    途径

    Stem Cell Maintenance
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