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NOTCH4 抗体

This anti-NOTCH4 antibody is a 兔 多克隆 antibody detecting NOTCH4 in WB. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7264327
发货至: 中国

Quick Overview for NOTCH4 抗体 (ABIN7264327)

抗原

See all NOTCH4 抗体
NOTCH4 (Notch 4 (NOTCH4))

适用

  • 43
  • 28
  • 21
  • 4
  • 4
  • 4
  • 3
  • 3
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 57
  • 3
  • 2
  • 2

克隆类型

  • 51
  • 13
多克隆

标记

  • 36
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This NOTCH4 antibody is un-conjugated

应用范围

  • 31
  • 20
  • 13
  • 13
  • 11
  • 9
  • 5
  • 4
  • 4
  • 3
  • 2
  • 2
Western Blotting (WB)
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein of human NOTCH4 (NP_004548.3).

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    NOTCH4 (Notch 4 (NOTCH4))

    别名

    NOTCH4

    背景

    This gene encodes a member of the NOTCH family of proteins. Members of this Type I transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple different domain types. Notch signaling is an evolutionarily conserved intercellular signaling pathway that regulates interactions between physically adjacent cells through binding of Notch family receptors to their cognate ligands. The encoded preproprotein is proteolytically processed in the trans-Golgi network to generate two polypeptide chains that heterodimerize to form the mature cell-surface receptor. This receptor may play a role in vascular, renal and hepatic development. Mutations in this gene may be associated with schizophrenia. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

    分子量

    Observed_MW: 88 kDa

    Calculated_MW: 39 kDa/61 kDa/209 kDa

    基因ID

    4855

    UniProt

    Q99466

    途径

    Notch Signaling
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