Cofilin 2 抗体
Quick Overview for Cofilin 2 抗体 (ABIN7264069)
抗原
See all Cofilin 2 (CFL2) 抗体适用
宿主
克隆类型
标记
应用范围
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产品特性
- Polyclonal Antibody
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein of human CFL2 (NP_068733.1).
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亚型
- IgG
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应用备注
- WB 1:500-1:2000 IF 1:50-1:100
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- Cofilin 2 (CFL2)
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别名
- CFL2
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背景
- This gene encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. This protein is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH -dependent manner. Mutations in this gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants.
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分子量
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Observed_MW: 18 kDa
Calculated_MW: 16 kDa/18 kDa
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基因ID
- 1073
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UniProt
- Q9Y281
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途径
- Caspase Cascade in Apoptosis
抗原
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