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GLUD1 抗体

This anti-GLUD1 antibody is a 兔 多克隆 antibody detecting GLUD1 in IHC 和 IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7263621
发货至: 中国

Quick Overview for GLUD1 抗体 (ABIN7263621)

抗原

See all GLUD1 抗体
GLUD1 (Glutamate Dehydrogenase 1 (GLUD1))

适用

  • 35
  • 19
  • 17
  • 17
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 47
  • 6
  • 1

克隆类型

  • 46
  • 8
多克隆

标记

  • 38
  • 5
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This GLUD1 antibody is un-conjugated

应用范围

  • 41
  • 27
  • 19
  • 16
  • 15
  • 10
  • 6
  • 5
  • 5
  • 4
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein of human GLUD1 (NP_005262.1).

    亚型

    IgG
  • 应用备注

    IHC 1:100-1:200 IF 1:50-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    GLUD1 (Glutamate Dehydrogenase 1 (GLUD1))

    别名

    GLUD1

    背景

    This gene encodes glutamate dehydrogenase, which is a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid-induced insulin secretion. It is allosterically activated by ADP and inhibited by GTP and ATP. Activating mutations in this gene are a common cause of congenital hyperinsulinism. Alternative splicing of this gene results in multiple transcript variants. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Related pseudogenes have been identified on chromosomes 10, 18 and X.

    基因ID

    2746

    UniProt

    P00367

    途径

    Positive Regulation of Peptide Hormone Secretion, Warburg Effect
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