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MUS81 抗体

This anti-MUS81 antibody is a 兔 多克隆 antibody detecting MUS81 in IHC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7262745
发货至: 中国

Quick Overview for MUS81 抗体 (ABIN7262745)

抗原

See all MUS81 抗体
MUS81 (MUS81 Endonuclease Homolog (MUS81))

适用

  • 18
  • 6
  • 5
  • 2
  • 2
  • 1
人, 小鼠, 大鼠

宿主

  • 17
  • 1

克隆类型

  • 18
多克隆

标记

  • 14
  • 2
  • 1
  • 1
This MUS81 antibody is un-conjugated

应用范围

  • 12
  • 8
  • 5
  • 3
  • 1
  • 1
Immunohistochemistry (IHC)
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein of human MUS81 (NP_079404.3).

    亚型

    IgG
  • 应用备注

    IHC 1:50-1:100

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    MUS81 (MUS81 Endonuclease Homolog (MUS81))

    别名

    MUS81

    背景

    This gene encodes a structure-specific endonuclease which belongs to the XPF/MUS81 endonuclease family and plays a critical role in the resolution of recombination intermediates during DNA repair after inter-strand cross-links, replication fork collapse, and DNA double-strand breaks. The encoded protein associates with one of two closely related essential meiotic endonuclease proteins (EME1 or EME2) to form a complex that processes DNA secondary structures. It contains an N-terminal DEAH helicase domain, an excision repair cross complementation group 4 (ERCC4) endonuclease domain, and two tandem C-terminal helix-hairpin-helix domains. Mice with a homozygous knockout of the orthologous gene have significant meiotic defects including the failure to repair a subset of DNA double strand breaks.

    基因ID

    80198

    UniProt

    Q96NY9

    途径

    DNA Damage Repair
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