IREB2 抗体
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北京 101111
Quick Overview for IREB2 抗体 (ABIN7262188)
抗原
See all IREB2 抗体适用
宿主
克隆类型
标记
应用范围
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产品特性
- Polyclonal Antibody
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein of human IREB2 (NP_004127.1).
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亚型
- IgG
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anti-Iron-Responsive Element Binding Protein 2 (IREB2) (AA 39-281) antibody
IREB2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Iron-Responsive Element Binding Protein 2 (IREB2) (AA 1-250) antibodyIREB2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Iron-Responsive Element Binding Protein 2 (IREB2) (AA 107-216) antibodyIREB2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Iron-Responsive Element Binding Protein 2 (IREB2) (Internal Region) antibodyVerified IREB2 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Iron-Responsive Element Binding Protein 2 (IREB2) (AA 1-343) antibodyIREB2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1F3 unconjugated
anti-Iron-Responsive Element Binding Protein 2 (IREB2) (AA 1-343) antibodyIREB2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Iron-Responsive Element Binding Protein 2 (IREB2) (AA 201-230) antibodyIREB2 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB30212 unconjugated
anti-Iron-Responsive Element Binding Protein 2 (IREB2) (Middle Region) antibodyIREB2 适用: 人, 大鼠, 小鼠, Pig, 犬, 马, 豚鼠, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Iron-Responsive Element Binding Protein 2 (IREB2) (AA 208-238), (Middle Region) antibodyIREB2 适用: 人 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Iron-Responsive Element Binding Protein 2 (IREB2) (AA 1-343) antibodyIREB2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- IF 1:20-1:50
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- IREB2 (Iron-Responsive Element Binding Protein 2 (IREB2))
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别名
- IREB2
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背景
- The protein encoded by this gene is an RNA-binding protein that acts to regulate iron levels in the cells by regulating the translation and stability of mRNAs that affect iron homeostasis under conditions when iron is depleted. When iron levels are low, this protein binds to iron-responsive elements (IRES), stem-loop structures located either in the 5' or 3' UTRs. Binding to the 5' UTR represses translation, while binding to the 3' UTR inhibits mRNA degradation. When iron is found in the cell, this protein is degraded in a F-box and leucine rich repeat protein 5-dependent manner. Variants in this gene have been associated with lung cancer and chronic obstructive pulmonary disease (COPD). Alternative splicing results in multiple transcript variants encoding different isoforms.
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基因ID
- 3658
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UniProt
- P48200
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途径
- Transition Metal Ion Homeostasis
抗原
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