Cullin 2 抗体
Quick Overview for Cullin 2 抗体 (ABIN7260691)
抗原
See all Cullin 2 (CUL2) 抗体适用
宿主
克隆类型
标记
应用范围
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产品特性
- Polyclonal Antibody
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein of human CUL2 (NP_001185708.1).
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亚型
- IgG
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anti-Cullin 2 (CUL2) (C-Term) antibody
CUL2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cullin 2 (CUL2) (C-Term) antibodyCUL2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cullin 2 (CUL2) (AA 591-742) antibodyCUL2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cullin 2 (CUL2) (AA 1-100) antibodyCUL2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Cullin 2 (CUL2) (C-Term) antibodyCUL2 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cullin 2 (CUL2) (AA 1-100) antibodyCUL2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4G11 unconjugated
anti-Cullin 2 (CUL2) (C-Term) antibodyVerified CUL2 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Cullin 2 (CUL2) (AA 40-310) antibodyCUL2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Cullin 2 (CUL2) (AA 264-280), (Middle Region) antibodyCUL2 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Cullin 2 (CUL2) (AA 696-745) antibodyCUL2 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- IHC 1:50-1:200 IF 1:50-1:200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- Cullin 2 (CUL2)
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别名
- CUL2
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背景
- Human CUL2 is an ortholog of nematode cul2. Michel and Xiong (1998) identified human CUL2 cDNAs and reported that the predicted protein is 745 amino acids long.Core component of multiple cullin-RING-based ECS (ElonginB/C-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, whicHuman, Mouseediate the ubiquitination of target proteins. May serve as a rigid scaffold in the complex and may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit and is inhibited by the association of the deneddylated cullin subunit with TIP120A/CAND1 By similarity. The functional specificity of the ECS complex depends on the substrate recognition component. ECS(VHL) mediates the ubiquitination of hypoxia-inducible factor (HIF).
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基因ID
- 8453
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UniProt
- Q13617
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途径
- M Phase, Asymmetric Protein Localization, SARS-CoV-2 Protein Interactome
抗原
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