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PGC 抗体

This anti-PGC antibody is a 兔 多克隆 antibody detecting PGC in WB. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN7260655
发货至: 中国

Quick Overview for PGC 抗体 (ABIN7260655)

抗原

See all PGC 抗体
PGC (Pepsinogen C (PGC))

适用

  • 83
  • 23
  • 14
  • 2
  • 1
  • 1
  • 1
  • 1
人, 大鼠, 小鼠

宿主

  • 74
  • 29
  • 2

克隆类型

  • 78
  • 27
多克隆

标记

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  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This PGC antibody is un-conjugated

应用范围

  • 61
  • 42
  • 29
  • 25
  • 17
  • 13
  • 13
  • 7
  • 5
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB)
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Affinity purification

    免疫原

    A synthetic peptide of human Pepsinogen II (NP_001159896.1).

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    PGC (Pepsinogen C (PGC))

    别名

    Pepsinogen II

    背景

    This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1.

    分子量

    Observed_MW: 45-50 kDa

    Calculated_MW: 34 kDa/42 kDa

    基因ID

    5225

    UniProt

    P20142
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