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ZYX 抗体

This anti-ZYX antibody is a 兔 多克隆 antibody detecting ZYX in WB, IHC 和 IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7260207
发货至: 中国

Quick Overview for ZYX 抗体 (ABIN7260207)

抗原

See all ZYX 抗体
ZYX (Zyxin (ZYX))

适用

  • 65
  • 23
  • 15
  • 4
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 53
  • 11
  • 1

克隆类型

  • 48
  • 16
多克隆

标记

  • 36
  • 7
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
This ZYX antibody is un-conjugated

应用范围

  • 44
  • 20
  • 16
  • 14
  • 13
  • 12
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein of human ZYX (NP_001010972.1).

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    ZYX (Zyxin (ZYX))

    别名

    ZYX

    背景

    Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform.

    分子量

    Observed_MW: 78 kDa

    Calculated_MW: 45 kDa/61 kDa

    基因ID

    7791

    UniProt

    Q15942
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