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UBE2D1 抗体

This anti-UBE2D1 antibody is a 兔 多克隆 antibody detecting UBE2D1 in WB 和 IHC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7259985
发货至: 中国

Quick Overview for UBE2D1 抗体 (ABIN7259985)

抗原

See all UBE2D1 抗体
UBE2D1 (Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1))

适用

  • 49
  • 22
  • 14
  • 4
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 46
  • 3

克隆类型

  • 43
  • 6
多克隆

标记

  • 19
  • 4
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This UBE2D1 antibody is un-conjugated

应用范围

  • 38
  • 18
  • 13
  • 13
  • 12
  • 9
  • 3
  • 2
  • 2
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein of human UBE2D1 (NP_003329.1).

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000 IHC 1:50-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    UBE2D1 (Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1))

    别名

    UBE2D1

    背景

    The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases. Two transcript variants encoding different isoforms have been found for this gene.

    分子量

    Observed_MW: 14 kDa

    Calculated_MW: 16 kDa

    基因ID

    7321

    UniProt

    P51668

    途径

    Activation of Innate immune Response, Toll-Like Receptors Cascades
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