UBE2D1 抗体
Quick Overview for UBE2D1 抗体 (ABIN7259985)
抗原
See all UBE2D1 抗体适用
宿主
克隆类型
标记
应用范围
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产品特性
- Polyclonal Antibody
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein of human UBE2D1 (NP_003329.1).
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亚型
- IgG
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应用备注
- WB 1:500-1:2000 IHC 1:50-1:200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- UBE2D1 (Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1))
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别名
- UBE2D1
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背景
- The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases. Two transcript variants encoding different isoforms have been found for this gene.
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分子量
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Observed_MW: 14 kDa
Calculated_MW: 16 kDa
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基因ID
- 7321
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UniProt
- P51668
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途径
- Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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