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DMP1 抗体

DMTF1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7259548
发货至: 中国
  • 抗原 See all DMP1 (DMTF1) 抗体
    DMP1 (DMTF1) (Cyclin D Binding Myb-Like Transcription Factor 1 (DMTF1))
    适用
    • 82
    • 19
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    宿主
    • 71
    • 8
    • 3
    • 1
    克隆类型
    • 76
    • 7
    多克隆
    标记
    • 37
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    • 1
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    This DMP1 antibody is un-conjugated
    应用范围
    • 57
    • 33
    • 26
    • 26
    • 8
    • 6
    • 5
    • 4
    • 1
    • 1
    Western Blotting (WB)
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein of human DMTF1 (NP_066968.3).
    亚型
    IgG
    Top Product
    Discover our top product DMTF1 Primary Antibody
  • 应用备注
    WB 1:500-1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    DMP1 (DMTF1) (Cyclin D Binding Myb-Like Transcription Factor 1 (DMTF1))
    别名
    DMTF1 (DMTF1 产品)
    背景
    This gene encodes a transcription factor that contains a cyclin D-binding domain, three central Myb-like repeats, and two flanking acidic transactivation domains at the N- and C-termini. The encoded protein is induced by the oncogenic Ras signaling pathway and functions as a tumor suppressor by activating the transcription of ARF and thus the ARF-p53 pathway to arrest cell growth or induce apoptosis. It also activates the transcription of aminopeptidase N and may play a role in hematopoietic cell differentiation. The transcriptional activity of this protein is regulated by binding of D-cyclins. This gene is hemizygously deleted in approximately 40 % of human non-small-cell lung cancer and is a potential prognostic and gene-therapy target for non-small-cell lung cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
    分子量

    Observed_MW: 85 kDa

    Calculated_MW: 84 kDa

    基因ID
    9988
    UniProt
    Q9Y222
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