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IL4 Receptor 抗体

This anti-IL4 Receptor antibody is a 兔 多克隆 antibody detecting IL4 Receptor in IHC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7258016
发货至: 中国

Quick Overview for IL4 Receptor 抗体 (ABIN7258016)

抗原

See all IL4 Receptor (IL4R) 抗体
IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))

适用

人, 小鼠, 大鼠

宿主

  • 81
  • 12
  • 2
  • 2
  • 2
  • 1

克隆类型

  • 85
  • 12
  • 2
多克隆

标记

  • 52
  • 10
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This IL4 Receptor antibody is un-conjugated

应用范围

  • 84
  • 30
  • 28
  • 22
  • 14
  • 14
  • 13
  • 11
  • 9
  • 8
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Immunohistochemistry (IHC)
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein of human IL4R (NP_000409.1).

    亚型

    IgG
  • 应用备注

    IHC 1:50-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))

    别名

    IL4R

    背景

    This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection. Alternate splicing results in multiple transcript variants.

    基因ID

    3566

    UniProt

    P24394

    途径

    JAK/STAT Signaling, Positive Regulation of Immune Effector Process
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