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DNASE1 抗体

This anti-DNASE1 antibody is a 兔 多克隆 antibody detecting DNASE1 in IF. Suitable for 大鼠 和 小鼠.
产品编号 ABIN7257934
发货至: 中国

Quick Overview for DNASE1 抗体 (ABIN7257934)

抗原

See all DNASE1 抗体
DNASE1 (Deoxyribonuclease I (DNASE1))

适用

  • 70
  • 25
  • 17
  • 15
大鼠, 小鼠

宿主

  • 68
  • 17
  • 1

克隆类型

  • 71
  • 15
多克隆

标记

  • 44
  • 12
  • 9
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This DNASE1 antibody is un-conjugated

应用范围

  • 74
  • 30
  • 25
  • 15
  • 14
  • 13
  • 13
  • 11
  • 8
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Immunofluorescence (IF)
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein of human DNASE1 (NP_005214.2).

    亚型

    IgG
  • 应用备注

    IF 1:50-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    DNASE1 (Deoxyribonuclease I (DNASE1))

    别名

    DNASE1

    背景

    This gene encodes a member of the DNase family. This protein is stored in the zymogen granules of the nuclear envelope and functions by cleaving DNA in an endonucleolytic manner. At least six autosomal codominant alleles have been characterized, DNASE1*1 through DNASE1*6, and the sequence of DNASE1*2 represented in this record. Mutations in this gene have been associated with systemic lupus erythematosus (SLE), an autoimmune disease. A recombinant form of this protein is used to treat the one of the symptoms of cystic fibrosis by hydrolyzing the extracellular DNA in sputum and reducing its viscosity. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.

    基因ID

    1773

    UniProt

    P24855
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