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Dystrophin 抗体

This anti-Dystrophin antibody is a 兔 多克隆 antibody detecting Dystrophin in IHC, WB 和 IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7008615
发货至: 中国

Quick Overview for Dystrophin 抗体 (ABIN7008615)

抗原

See all Dystrophin (DMD) 抗体
Dystrophin (DMD)

适用

  • 107
  • 16
  • 14
  • 2
人, 小鼠, 大鼠

宿主

  • 73
  • 36

克隆类型

  • 83
  • 26
多克隆

标记

  • 51
  • 7
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
This Dystrophin antibody is un-conjugated

应用范围

  • 82
  • 50
  • 31
  • 16
  • 15
  • 13
  • 6
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF)
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein of human DMD (NP_004007.1).

    亚型

    IgG
  • 应用备注

    WB 1:200-1:2000 IHC 1:50-1:200 IF 1:50-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    Dystrophin (DMD)

    别名

    DMD

    背景

    This gene spans a genomic range of greater than 2 Mb and encodes a large protein containing an N-terminal actin-binding domain and multiple spectrin repeats. The encoded protein forms a component of the dystrophin-glycoprotein complex (DGC), which bridges the inner cytoskeleton and the extracellular matrix. Deletions, duplications, and point mutations at this gene locus may cause Duchenne muscular dystrophy (DMD), Becker muscular dystrophy (BMD), or cardiomyopathy. Alternative promoter usage and alternative splicing result in numerous distinct transcript variants and protein isoforms for this gene.

    分子量

    Observed_MW: 427 kDa

    Calculated_MW: 57-72 kDa/271 kDa/425-426 kDa

    基因ID

    1756

    UniProt

    P11532

    途径

    Skeletal Muscle Fiber Development
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