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KLHL3 抗体

The 兔 多克隆 anti-KLHL3 antibody is suitable to detect KLHL3 in samples from 人 和 小鼠. It has been validated for WB.
产品编号 ABIN7257377
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for KLHL3 抗体 (ABIN7257377)

抗原

See all KLHL3 抗体
KLHL3 (Kelch-Like 3 (KLHL3))

适用

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人, 小鼠

宿主

  • 50
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克隆类型

  • 52
多克隆

标记

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This KLHL3 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein of human KLHL3 (NP_059111.2).

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    KLHL3 (Kelch-Like 3 (KLHL3))

    别名

    KLHL3

    背景

    This gene is ubiquitously expressed and encodes a full-length protein which has an N-terminal BTB domain followed by a BACK domain and six kelch-like repeats in the C-terminus. These kelch-like repeats promote substrate ubiquitination of bound proteins via interaction of the BTB domain with the CUL3 (cullin 3) component of a cullin-RING E3 ubiquitin ligase (CRL) complex. Muatations in this gene cause pseudohypoaldosteronism type IID (PHA2D), a rare Mendelian syndrome featuring hypertension, hyperkalaemia and metabolic acidosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

    分子量

    Observed_MW: 75 kDa

    Calculated_MW: 55 kDa/61 kDa/64 kDa

    基因ID

    26249

    UniProt

    Q9UH77
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